Identification and evaluation of pyrimidine based CDK6 inhibitors against glioblastoma using integrated computational approaches.

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Title: Identification and evaluation of pyrimidine based CDK6 inhibitors against glioblastoma using integrated computational approaches.
Authors: Manzoor H; Institute of Molecular Biology and Biotechnology, The University of Lahore, Lahore, Pakistan., Khan MU; Institute of Molecular Biology and Biotechnology, The University of Lahore, Lahore, Pakistan. muhammad.umer4@mlt.uol.edu.pk., Rehman R; Centre of Excellence in Molecular Biology, University of the Punjab, Lahore, Pakistan., Shabbir CA; Faculty of Medical and Health Sciences, The University of Adelaide, Adelaide, SA, 5005, Australia., Ullah MI; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Jouf University, Sakaka, Aljouf, 72388, Saudi Arabia., Ghanem HB; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Jouf University, Sakaka, Aljouf, 72388, Saudi Arabia., Alameen AAM; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Jouf University, Sakaka, Aljouf, 72388, Saudi Arabia., Javed MA; Department of Plant Breeding and Genetics, Faculty of Agricultural Sciences, University of the Punjab, Lahore, Pakistan., Ali Q; Department of Plant Breeding and Genetics, Faculty of Agricultural Sciences, University of the Punjab, Lahore, Pakistan. saim1692@gmail.com., Haider N; Department of Pathology, College of Medicine, King Khalid University, Abha, 62529, Saudi Arabia.
Source: Scientific reports [Sci Rep] 2025 Jul 14; Vol. 15 (1), pp. 25387. Date of Electronic Publication: 2025 Jul 14.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2045-2322
DOI:10.1038/s41598-025-10744-1