The Effects of Daridorexant on Patients With Comorbid Insomnia Disorder and Untreated Mild Obstructive Sleep Apnoea: A Post Hoc Subgroup Analysis of a Phase 3, Randomised Clinical Trial.

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Title: The Effects of Daridorexant on Patients With Comorbid Insomnia Disorder and Untreated Mild Obstructive Sleep Apnoea: A Post Hoc Subgroup Analysis of a Phase 3, Randomised Clinical Trial.
Authors: Lettieri CJ; Idorsia Pharmaceuticals US Ltd, Radnor, Pennsylvania, USA.; Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, Uniformed Services University, Bethesda, Maryland, USA., Briasoulis O; Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland., Léger D; VIFASOM (Vigilance Fatigue et Santé Publique), Université Paris Cité, Paris, France.; APHP, Hôtel Dieu de Paris, Centre du Sommeil et de la Vigilance, Paris, France., Luyet PP; Idorsia Pharmaceuticals Ltd, Allschwil, Switzerland., Pépin JL; Grenoble Alpes University, Grenoble, France., Quan SF; Division of Sleep and Circadian Disorders, Department of Medicine, Brigham and Women's Hospital and Division of Sleep Medicine, Harvard Medical School, Boston, Massachusetts, USA., Raphelson J; Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of California, San Diego, San Diego, California, USA., Saskin P; Idorsia Pharmaceuticals US Ltd, Radnor, Pennsylvania, USA., Malhotra A; Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of California, San Diego, San Diego, California, USA.
Source: Journal of sleep research [J Sleep Res] 2026 Apr; Vol. 35 (2), pp. e70135. Date of Electronic Publication: 2025 Jul 14.
Publication Type: Journal Article; Clinical Trial, Phase III; Randomized Controlled Trial
Journal Info: Publisher: Published on behalf of the European Sleep Research Society by Blackwell Scientific Publications Country of Publication: England NLM ID: 9214441 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2869 (Electronic) Linking ISSN: 09621105 NLM ISO Abbreviation: J Sleep Res Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1365-2869
DOI:10.1111/jsr.70135