Relaxin-2-secreting CAR-T cells exhibit enhanced efficacy in stromal-rich xenograft tumors.

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Title: Relaxin-2-secreting CAR-T cells exhibit enhanced efficacy in stromal-rich xenograft tumors.
Authors: Ogawa H; Nitto Joint Research Department for Nucleic Acid Medicine, Research Center, Osaka International Cancer Institute, Osaka, Japan., Ekawa T; Department of Cancer Drug Discovery and Development, Research Center, Osaka International Cancer Institute, Osaka, Japan., Mizote Y; Department of Cancer Drug Discovery and Development, Research Center, Osaka International Cancer Institute, Osaka, Japan., Akazawa T; Department of Cancer Drug Discovery and Development, Research Center, Osaka International Cancer Institute, Osaka, Japan., Tahara H; Department of Cancer Drug Discovery and Development, Research Center, Osaka International Cancer Institute, Osaka, Japan.; Center for Clinical Research, Osaka International Cancer Institute, Osaka, Japan.
Source: Frontiers in immunology [Front Immunol] 2025 Jul 01; Vol. 16, pp. 1506204. Date of Electronic Publication: 2025 Jul 01 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1664-3224
DOI:10.3389/fimmu.2025.1506204