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Cimicifuga foetida and C. racemosa prevent postmenopausal osteoporosis by inhibiting autophagy of osteoclasts via CB2R and ERα.

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Title: Cimicifuga foetida and C. racemosa prevent postmenopausal osteoporosis by inhibiting autophagy of osteoclasts via CB2R and ERα.
Authors: Hu SJ; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, PR China; School of Pharmacy, Naval Medical University, Shanghai 200433, PR China., Zhao ZH; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, PR China., Chen GC; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, PR China., Shan MY; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, PR China., Shen Y; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, PR China., Song ZL; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, PR China., Zhao QM; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, PR China., Cheng G; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, PR China., Zhang QL; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, PR China., Han T; School of Pharmacy, Naval Medical University, Shanghai 200433, PR China. Electronic address: hanting@smmu.edu.cn., Zhang QY; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, PR China; School of Pharmacy, Naval Medical University, Shanghai 200433, PR China. Electronic address: zqy1965@163.com., Qin LP; School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, PR China. Electronic address: lpqin@zcmu.edu.cn.
Source: Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2025 Sep; Vol. 145, pp. 157073. Date of Electronic Publication: 2025 Jul 13.
Publication Type: Journal Article
Journal Info: Publisher: Urban & Fischer Verlag Country of Publication: Germany NLM ID: 9438794 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1618-095X (Electronic) Linking ISSN: 09447113 NLM ISO Abbreviation: Phytomedicine Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1618-095X
DOI:10.1016/j.phymed.2025.157073