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Intravenous Thrombolysis in Patients With Recent Intake of Direct Oral Anticoagulants: A Target Trial Analysis and Comparison With Reversal Agent Use.

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Title: Intravenous Thrombolysis in Patients With Recent Intake of Direct Oral Anticoagulants: A Target Trial Analysis and Comparison With Reversal Agent Use.
Authors: Meinel TR; Department of Neurology, Stroke Research Center Bern (T.R.M., P.B., F.Z.-M., U.F., D.J.S.), Inselspital, Bern University Hospital, University of Bern, Switzerland., Bücke P; Department of Neurology, Stroke Research Center Bern (T.R.M., P.B., F.Z.-M., U.F., D.J.S.), Inselspital, Bern University Hospital, University of Bern, Switzerland., D'Anna L; Division of Brain Sciences, Imperial College London, United Kingdom (L.D.)., Merlino G; Clinical Neurology and Stroke Unit, Department of Head, Neck and Neurosciences, Udine University Hospital, Italy (G.M., A.B., L.C., M.V.)., Aguiar de Sousa D; Stroke Centre, Lisbon Central University Hospital Center-ULS São José, Portugal (D.A.d.S., M.E.M., C.G.).; CEEM e Instituto de Anatomia, Faculdade de Medicina, Universidade de Lisboa, Portugal (D.A.d.S., M.E.M., C.G.).; Gulbenkian Institute for Molecular Medicine, Lisbon, Portugal (D.A.d.S., M.E.M., C.G.)., Poli S; Department of Neurology and Stroke (S.P., A.G.-E.), University of Tübingen, Germany.; Hertie Institute for Clinical Brain Research (S.P., A.G.-E.), University of Tübingen, Germany., Purrucker JC; Department of Neurology, Heidelberg University Hospital, Germany (J.C.P., A.K.)., Strambo D; Stroke Center, Neurology Service, Department of Clinical Neurosciences, Lausanne University Hospital and University of Lausanne, Switzerland (D.S., G.T., P.M.)., Romoli M; Neurology and Stroke Unit, Department of Neurosciences, Bufalini Hospital, AUSL Romagna, Cesena, Italy (M.R., G.S.)., De Marchis GM; Department of Neurology and Stroke Center, University Research and Teaching Hospital, Cantonal Hospital St. Gallen, Switzerland (G.M.D.M., D.V.).; Medical Faculty, University of Basel, Switzerland (G.M.D.M., D.V.)., Pfeilschifter W; Department of Neurology and Clinical Neurophysiology, Klinikum Lueneburg, Germany (W.P., M. Herrmann)., Zedde M; Neurology Unit, Stroke Unit, Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia, Italy (M.Z.)., Marto JP; Department of Neurology, Centro Hospitalar Lisboa Ocidental, Hospital de Egas Moniz, Lisbon, Portugal (J.P.M., B.R.)., Candelaresi P; Neurology and Stroke Unit, A.O.R.N. Antonio Cardarelli, Napoli, Italy (P.C., E.S., V.A.)., Lemmens R; Department of Neurosciences, Experimental Neurology, KU Leuven, Belgium (R.L., L.M.).; Department of Neurology, University Hospitals Leuven, Belgium (R.L., L.M.)., Scoppettuolo P; Neurology Department, Cliniques Universitaires Saint Luc-UCL, Bruxelles, Belgique (P.S.)., Woock M; Department of Neurology, Sahlgrenska University Hospital, Göteborg, Sweden (M.W., A.A.)., Kermer P; Department of Neurology, Nordwest-Krankenhaus Sanderbusch, Friesland Kliniken GmbH, Sande and University Medicine Göttingen, Germany (P.K.)., Kristoffersen ES; Department of Neurology, Akershus University Hospital, Lørenskog, Norway (E.S.K.)., Ghannam M; Department of Neurology, University of Iowa Hospitals and Clinics (M.G., Q.N.A.)., Frol S; Department of Vascular Neurology, University Medical Center Ljubljana, Faculty of Medicine, University of Ljubljana, Slovenia (S.F.)., Nolte CH; Department of Neurology with Experimental Neurology and Center for Stroke Research, Charité-Universitätsmedizin Berlin, Germany (C.H.N., C.R.)., Yakushiji Y; Department of Neurology, Kansai Medical University, Osaka, Japan (Y.Y., T.K.)., Touzé E; Department of Neurology, CHU de Caen Normandie, France (E.T., M.B.)., Uphaus T; Department of Neurology, Focus Program Translational Neuroscience (FTN) and Immunotherapy (FZI), Rhine Main Neuroscience Network (rmn2), University Medical Center of the Johannes Gutenberg-University, Mainz, Germany (T.U., M. Hahn)., Mannino M; Department of Neurology and Stroke Unit, AOOR Villa Sofia-V. Cervello, Palermo, Italy (M.M.)., Ntaios G; 1 Propaedeutic Department of Internal Medicine, AHEPA University Hospital, Aristotle University of Thessaloniki, Greece (G.N., D.P.)., Padjen V; Neurology Clinic, Clinical Centre of Serbia, Faculty of Medicine, University of Belgrade, Serbia (V.P.)., Henninger N; Department of Neurology, University of Massachusetts Chan Medical School, Worcester (N.H., J.M.)., Zipser-Mohammadzada F; Department of Neurology, Stroke Research Center Bern (T.R.M., P.B., F.Z.-M., U.F., D.J.S.), Inselspital, Bern University Hospital, University of Bern, Switzerland., Mariano ME; Stroke Centre, Lisbon Central University Hospital Center-ULS São José, Portugal (D.A.d.S., M.E.M., C.G.).; CEEM e Instituto de Anatomia, Faculdade de Medicina, Universidade de Lisboa, Portugal (D.A.d.S., M.E.M., C.G.).; Gulbenkian Institute for Molecular Medicine, Lisbon, Portugal (D.A.d.S., M.E.M., C.G.)., Guerreiro C; Stroke Centre, Lisbon Central University Hospital Center-ULS São José, Portugal (D.A.d.S., M.E.M., C.G.).; CEEM e Instituto de Anatomia, Faculdade de Medicina, Universidade de Lisboa, Portugal (D.A.d.S., M.E.M., C.G.).; Gulbenkian Institute for Molecular Medicine, Lisbon, Portugal (D.A.d.S., M.E.M., C.G.)., Burini A; Clinical Neurology and Stroke Unit, Department of Head, Neck and Neurosciences, Udine University Hospital, Italy (G.M., A.B., L.C., M.V.)., Ceccarelli L; Clinical Neurology and Stroke Unit, Department of Head, Neck and Neurosciences, Udine University Hospital, Italy (G.M., A.B., L.C., M.V.)., Valente M; Clinical Neurology and Stroke Unit, Department of Head, Neck and Neurosciences, Udine University Hospital, Italy (G.M., A.B., L.C., M.V.)., Gomez-Exposito A; Department of Neurology and Stroke (S.P., A.G.-E.), University of Tübingen, Germany.; Hertie Institute for Clinical Brain Research (S.P., A.G.-E.), University of Tübingen, Germany., Kleeberg A; Department of Neurology, Heidelberg University Hospital, Germany (J.C.P., A.K.)., Thevoz G; Stroke Center, Neurology Service, Department of Clinical Neurosciences, Lausanne University Hospital and University of Lausanne, Switzerland (D.S., G.T., P.M.)., Michel P; Stroke Center, Neurology Service, Department of Clinical Neurosciences, Lausanne University Hospital and University of Lausanne, Switzerland (D.S., G.T., P.M.)., Stufano G; Neurology and Stroke Unit, Department of Neurosciences, Bufalini Hospital, AUSL Romagna, Cesena, Italy (M.R., G.S.)., Vlachos D; Department of Neurology and Stroke Center, University Research and Teaching Hospital, Cantonal Hospital St. Gallen, Switzerland (G.M.D.M., D.V.).; Medical Faculty, University of Basel, Switzerland (G.M.D.M., D.V.)., Herrmann M; Department of Neurology and Clinical Neurophysiology, Klinikum Lueneburg, Germany (W.P., M. Herrmann)., Rodrigues B; Department of Neurology, Centro Hospitalar Lisboa Ocidental, Hospital de Egas Moniz, Lisbon, Portugal (J.P.M., B.R.)., Spina E; Neurology and Stroke Unit, A.O.R.N. Antonio Cardarelli, Napoli, Italy (P.C., E.S., V.A.)., Andreone V; Neurology and Stroke Unit, A.O.R.N. Antonio Cardarelli, Napoli, Italy (P.C., E.S., V.A.)., Allardt A; Department of Neurology, Sahlgrenska University Hospital, Göteborg, Sweden (M.W., A.A.)., Alshaer QN; Department of Neurology, University of Iowa Hospitals and Clinics (M.G., Q.N.A.)., Riegler C; Department of Neurology with Experimental Neurology and Center for Stroke Research, Charité-Universitätsmedizin Berlin, Germany (C.H.N., C.R.)., Kunieda T; Department of Neurology, Kansai Medical University, Osaka, Japan (Y.Y., T.K.)., Boulanger M; Department of Neurology, CHU de Caen Normandie, France (E.T., M.B.)., Hahn M; Department of Neurology, Focus Program Translational Neuroscience (FTN) and Immunotherapy (FZI), Rhine Main Neuroscience Network (rmn2), University Medical Center of the Johannes Gutenberg-University, Mainz, Germany (T.U., M. Hahn)., Papadimitriou D; 1 Propaedeutic Department of Internal Medicine, AHEPA University Hospital, Aristotle University of Thessaloniki, Greece (G.N., D.P.)., Muppa J; Department of Neurology, University of Massachusetts Chan Medical School, Worcester (N.H., J.M.)., Maes L; Department of Neurosciences, Experimental Neurology, KU Leuven, Belgium (R.L., L.M.).; Department of Neurology, University Hospitals Leuven, Belgium (R.L., L.M.)., Ranta A; Department of Neurology, Wellington Hospital, New Zealand (A.R., A.T.)., Tyson A; Department of Neurology, Wellington Hospital, New Zealand (A.R., A.T.)., Barber PA; Department of Medicine, University of Auckland, New Zealand (P.A.B.)., Davis AJ; Department of Medicine, Whangarei Hospital, New Zealand (A.J.D.)., Wu TY; Department of Neurology, Christchurch Hospital, New Zealand (T.Y.W.)., Kaesmacher J; University Institute of Diagnostic and Interventional Neuroradiology (J.K.), Inselspital, Bern University Hospital, University of Bern, Switzerland.; Diagnostic and Interventional Neuroradiology, Tours, France (J.K.).; Le Studium Loire Valley Institute for Advanced Studies, Orléans, France (J.K.)., Fischer U; Department of Neurology, Stroke Research Center Bern (T.R.M., P.B., F.Z.-M., U.F., D.J.S.), Inselspital, Bern University Hospital, University of Bern, Switzerland., Seiffge DJ; Department of Neurology, Stroke Research Center Bern (T.R.M., P.B., F.Z.-M., U.F., D.J.S.), Inselspital, Bern University Hospital, University of Bern, Switzerland.
Corporate Authors: International DO-IT Collaboration
Source: Stroke [Stroke] 2025 Oct; Vol. 56 (10), pp. 2836-2845. Date of Electronic Publication: 2025 Jul 22.
Publication Type: Journal Article; Comparative Study; Multicenter Study
Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0235266 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1524-4628 (Electronic) Linking ISSN: 00392499 NLM ISO Abbreviation: Stroke Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Intravenous Thrombolysis in Patients With Recent Intake of Direct Oral Anticoagulants: A Target Trial Analysis and Comparison With Reversal Agent Use.
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  Data: <searchLink fieldCode="AU" term="%22Meinel+TR%22">Meinel TR</searchLink>; Department of Neurology, Stroke Research Center Bern (T.R.M., P.B., F.Z.-M., U.F., D.J.S.), Inselspital, Bern University Hospital, University of Bern, Switzerland.<br /><searchLink fieldCode="AU" term="%22Bücke+P%22">Bücke P</searchLink>; Department of Neurology, Stroke Research Center Bern (T.R.M., P.B., F.Z.-M., U.F., D.J.S.), Inselspital, Bern University Hospital, University of Bern, Switzerland.<br /><searchLink fieldCode="AU" term="%22D'Anna+L%22">D'Anna L</searchLink>; Division of Brain Sciences, Imperial College London, United Kingdom (L.D.).<br /><searchLink fieldCode="AU" term="%22Merlino+G%22">Merlino G</searchLink>; Clinical Neurology and Stroke Unit, Department of Head, Neck and Neurosciences, Udine University Hospital, Italy (G.M., A.B., L.C., M.V.).<br /><searchLink fieldCode="AU" term="%22Aguiar+de+Sousa+D%22">Aguiar de Sousa D</searchLink>; Stroke Centre, Lisbon Central University Hospital Center-ULS São José, Portugal (D.A.d.S., M.E.M., C.G.).; CEEM e Instituto de Anatomia, Faculdade de Medicina, Universidade de Lisboa, Portugal (D.A.d.S., M.E.M., C.G.).; Gulbenkian Institute for Molecular Medicine, Lisbon, Portugal (D.A.d.S., M.E.M., C.G.).<br /><searchLink fieldCode="AU" term="%22Poli+S%22">Poli S</searchLink>; Department of Neurology and Stroke (S.P., A.G.-E.), University of Tübingen, Germany.; Hertie Institute for Clinical Brain Research (S.P., A.G.-E.), University of Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Purrucker+JC%22">Purrucker JC</searchLink>; Department of Neurology, Heidelberg University Hospital, Germany (J.C.P., A.K.).<br /><searchLink fieldCode="AU" term="%22Strambo+D%22">Strambo D</searchLink>; Stroke Center, Neurology Service, Department of Clinical Neurosciences, Lausanne University Hospital and University of Lausanne, Switzerland (D.S., G.T., P.M.).<br /><searchLink fieldCode="AU" term="%22Romoli+M%22">Romoli M</searchLink>; Neurology and Stroke Unit, Department of Neurosciences, Bufalini Hospital, AUSL Romagna, Cesena, Italy (M.R., G.S.).<br /><searchLink fieldCode="AU" term="%22De+Marchis+GM%22">De Marchis GM</searchLink>; Department of Neurology and Stroke Center, University Research and Teaching Hospital, Cantonal Hospital St. Gallen, Switzerland (G.M.D.M., D.V.).; Medical Faculty, University of Basel, Switzerland (G.M.D.M., D.V.).<br /><searchLink fieldCode="AU" term="%22Pfeilschifter+W%22">Pfeilschifter W</searchLink>; Department of Neurology and Clinical Neurophysiology, Klinikum Lueneburg, Germany (W.P., M. Herrmann).<br /><searchLink fieldCode="AU" term="%22Zedde+M%22">Zedde M</searchLink>; Neurology Unit, Stroke Unit, Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia, Italy (M.Z.).<br /><searchLink fieldCode="AU" term="%22Marto+JP%22">Marto JP</searchLink>; Department of Neurology, Centro Hospitalar Lisboa Ocidental, Hospital de Egas Moniz, Lisbon, Portugal (J.P.M., B.R.).<br /><searchLink fieldCode="AU" term="%22Candelaresi+P%22">Candelaresi P</searchLink>; Neurology and Stroke Unit, A.O.R.N. Antonio Cardarelli, Napoli, Italy (P.C., E.S., V.A.).<br /><searchLink fieldCode="AU" term="%22Lemmens+R%22">Lemmens R</searchLink>; Department of Neurosciences, Experimental Neurology, KU Leuven, Belgium (R.L., L.M.).; Department of Neurology, University Hospitals Leuven, Belgium (R.L., L.M.).<br /><searchLink fieldCode="AU" term="%22Scoppettuolo+P%22">Scoppettuolo P</searchLink>; Neurology Department, Cliniques Universitaires Saint Luc-UCL, Bruxelles, Belgique (P.S.).<br /><searchLink fieldCode="AU" term="%22Woock+M%22">Woock M</searchLink>; Department of Neurology, Sahlgrenska University Hospital, Göteborg, Sweden (M.W., A.A.).<br /><searchLink fieldCode="AU" term="%22Kermer+P%22">Kermer P</searchLink>; Department of Neurology, Nordwest-Krankenhaus Sanderbusch, Friesland Kliniken GmbH, Sande and University Medicine Göttingen, Germany (P.K.).<br /><searchLink fieldCode="AU" term="%22Kristoffersen+ES%22">Kristoffersen ES</searchLink>; Department of Neurology, Akershus University Hospital, Lørenskog, Norway (E.S.K.).<br /><searchLink fieldCode="AU" term="%22Ghannam+M%22">Ghannam M</searchLink>; Department of Neurology, University of Iowa Hospitals and Clinics (M.G., Q.N.A.).<br /><searchLink fieldCode="AU" term="%22Frol+S%22">Frol S</searchLink>; Department of Vascular Neurology, University Medical Center Ljubljana, Faculty of Medicine, University of Ljubljana, Slovenia (S.F.).<br /><searchLink fieldCode="AU" term="%22Nolte+CH%22">Nolte CH</searchLink>; Department of Neurology with Experimental Neurology and Center for Stroke Research, Charité-Universitätsmedizin Berlin, Germany (C.H.N., C.R.).<br /><searchLink fieldCode="AU" term="%22Yakushiji+Y%22">Yakushiji Y</searchLink>; Department of Neurology, Kansai Medical University, Osaka, Japan (Y.Y., T.K.).<br /><searchLink fieldCode="AU" term="%22Touzé+E%22">Touzé E</searchLink>; Department of Neurology, CHU de Caen Normandie, France (E.T., M.B.).<br /><searchLink fieldCode="AU" term="%22Uphaus+T%22">Uphaus T</searchLink>; Department of Neurology, Focus Program Translational Neuroscience (FTN) and Immunotherapy (FZI), Rhine Main Neuroscience Network (rmn2), University Medical Center of the Johannes Gutenberg-University, Mainz, Germany (T.U., M. Hahn).<br /><searchLink fieldCode="AU" term="%22Mannino+M%22">Mannino M</searchLink>; Department of Neurology and Stroke Unit, AOOR Villa Sofia-V. Cervello, Palermo, Italy (M.M.).<br /><searchLink fieldCode="AU" term="%22Ntaios+G%22">Ntaios G</searchLink>; 1 Propaedeutic Department of Internal Medicine, AHEPA University Hospital, Aristotle University of Thessaloniki, Greece (G.N., D.P.).<br /><searchLink fieldCode="AU" term="%22Padjen+V%22">Padjen V</searchLink>; Neurology Clinic, Clinical Centre of Serbia, Faculty of Medicine, University of Belgrade, Serbia (V.P.).<br /><searchLink fieldCode="AU" term="%22Henninger+N%22">Henninger N</searchLink>; Department of Neurology, University of Massachusetts Chan Medical School, Worcester (N.H., J.M.).<br /><searchLink fieldCode="AU" term="%22Zipser-Mohammadzada+F%22">Zipser-Mohammadzada F</searchLink>; Department of Neurology, Stroke Research Center Bern (T.R.M., P.B., F.Z.-M., U.F., D.J.S.), Inselspital, Bern University Hospital, University of Bern, Switzerland.<br /><searchLink fieldCode="AU" term="%22Mariano+ME%22">Mariano ME</searchLink>; Stroke Centre, Lisbon Central University Hospital Center-ULS São José, Portugal (D.A.d.S., M.E.M., C.G.).; CEEM e Instituto de Anatomia, Faculdade de Medicina, Universidade de Lisboa, Portugal (D.A.d.S., M.E.M., C.G.).; Gulbenkian Institute for Molecular Medicine, Lisbon, Portugal (D.A.d.S., M.E.M., C.G.).<br /><searchLink fieldCode="AU" term="%22Guerreiro+C%22">Guerreiro C</searchLink>; Stroke Centre, Lisbon Central University Hospital Center-ULS São José, Portugal (D.A.d.S., M.E.M., C.G.).; CEEM e Instituto de Anatomia, Faculdade de Medicina, Universidade de Lisboa, Portugal (D.A.d.S., M.E.M., C.G.).; Gulbenkian Institute for Molecular Medicine, Lisbon, Portugal (D.A.d.S., M.E.M., C.G.).<br /><searchLink fieldCode="AU" term="%22Burini+A%22">Burini A</searchLink>; Clinical Neurology and Stroke Unit, Department of Head, Neck and Neurosciences, Udine University Hospital, Italy (G.M., A.B., L.C., M.V.).<br /><searchLink fieldCode="AU" term="%22Ceccarelli+L%22">Ceccarelli L</searchLink>; Clinical Neurology and Stroke Unit, Department of Head, Neck and Neurosciences, Udine University Hospital, Italy (G.M., A.B., L.C., M.V.).<br /><searchLink fieldCode="AU" term="%22Valente+M%22">Valente M</searchLink>; Clinical Neurology and Stroke Unit, Department of Head, Neck and Neurosciences, Udine University Hospital, Italy (G.M., A.B., L.C., M.V.).<br /><searchLink fieldCode="AU" term="%22Gomez-Exposito+A%22">Gomez-Exposito A</searchLink>; Department of Neurology and Stroke (S.P., A.G.-E.), University of Tübingen, Germany.; Hertie Institute for Clinical Brain Research (S.P., A.G.-E.), University of Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Kleeberg+A%22">Kleeberg A</searchLink>; Department of Neurology, Heidelberg University Hospital, Germany (J.C.P., A.K.).<br /><searchLink fieldCode="AU" term="%22Thevoz+G%22">Thevoz G</searchLink>; Stroke Center, Neurology Service, Department of Clinical Neurosciences, Lausanne University Hospital and University of Lausanne, Switzerland (D.S., G.T., P.M.).<br /><searchLink fieldCode="AU" term="%22Michel+P%22">Michel P</searchLink>; Stroke Center, Neurology Service, Department of Clinical Neurosciences, Lausanne University Hospital and University of Lausanne, Switzerland (D.S., G.T., P.M.).<br /><searchLink fieldCode="AU" term="%22Stufano+G%22">Stufano G</searchLink>; Neurology and Stroke Unit, Department of Neurosciences, Bufalini Hospital, AUSL Romagna, Cesena, Italy (M.R., G.S.).<br /><searchLink fieldCode="AU" term="%22Vlachos+D%22">Vlachos D</searchLink>; Department of Neurology and Stroke Center, University Research and Teaching Hospital, Cantonal Hospital St. Gallen, Switzerland (G.M.D.M., D.V.).; Medical Faculty, University of Basel, Switzerland (G.M.D.M., D.V.).<br /><searchLink fieldCode="AU" term="%22Herrmann+M%22">Herrmann M</searchLink>; Department of Neurology and Clinical Neurophysiology, Klinikum Lueneburg, Germany (W.P., M. Herrmann).<br /><searchLink fieldCode="AU" term="%22Rodrigues+B%22">Rodrigues B</searchLink>; Department of Neurology, Centro Hospitalar Lisboa Ocidental, Hospital de Egas Moniz, Lisbon, Portugal (J.P.M., B.R.).<br /><searchLink fieldCode="AU" term="%22Spina+E%22">Spina E</searchLink>; Neurology and Stroke Unit, A.O.R.N. Antonio Cardarelli, Napoli, Italy (P.C., E.S., V.A.).<br /><searchLink fieldCode="AU" term="%22Andreone+V%22">Andreone V</searchLink>; Neurology and Stroke Unit, A.O.R.N. Antonio Cardarelli, Napoli, Italy (P.C., E.S., V.A.).<br /><searchLink fieldCode="AU" term="%22Allardt+A%22">Allardt A</searchLink>; Department of Neurology, Sahlgrenska University Hospital, Göteborg, Sweden (M.W., A.A.).<br /><searchLink fieldCode="AU" term="%22Alshaer+QN%22">Alshaer QN</searchLink>; Department of Neurology, University of Iowa Hospitals and Clinics (M.G., Q.N.A.).<br /><searchLink fieldCode="AU" term="%22Riegler+C%22">Riegler C</searchLink>; Department of Neurology with Experimental Neurology and Center for Stroke Research, Charité-Universitätsmedizin Berlin, Germany (C.H.N., C.R.).<br /><searchLink fieldCode="AU" term="%22Kunieda+T%22">Kunieda T</searchLink>; Department of Neurology, Kansai Medical University, Osaka, Japan (Y.Y., T.K.).<br /><searchLink fieldCode="AU" term="%22Boulanger+M%22">Boulanger M</searchLink>; Department of Neurology, CHU de Caen Normandie, France (E.T., M.B.).<br /><searchLink fieldCode="AU" term="%22Hahn+M%22">Hahn M</searchLink>; Department of Neurology, Focus Program Translational Neuroscience (FTN) and Immunotherapy (FZI), Rhine Main Neuroscience Network (rmn2), University Medical Center of the Johannes Gutenberg-University, Mainz, Germany (T.U., M. Hahn).<br /><searchLink fieldCode="AU" term="%22Papadimitriou+D%22">Papadimitriou D</searchLink>; 1 Propaedeutic Department of Internal Medicine, AHEPA University Hospital, Aristotle University of Thessaloniki, Greece (G.N., D.P.).<br /><searchLink fieldCode="AU" term="%22Muppa+J%22">Muppa J</searchLink>; Department of Neurology, University of Massachusetts Chan Medical School, Worcester (N.H., J.M.).<br /><searchLink fieldCode="AU" term="%22Maes+L%22">Maes L</searchLink>; Department of Neurosciences, Experimental Neurology, KU Leuven, Belgium (R.L., L.M.).; Department of Neurology, University Hospitals Leuven, Belgium (R.L., L.M.).<br /><searchLink fieldCode="AU" term="%22Ranta+A%22">Ranta A</searchLink>; Department of Neurology, Wellington Hospital, New Zealand (A.R., A.T.).<br /><searchLink fieldCode="AU" term="%22Tyson+A%22">Tyson A</searchLink>; Department of Neurology, Wellington Hospital, New Zealand (A.R., A.T.).<br /><searchLink fieldCode="AU" term="%22Barber+PA%22">Barber PA</searchLink>; Department of Medicine, University of Auckland, New Zealand (P.A.B.).<br /><searchLink fieldCode="AU" term="%22Davis+AJ%22">Davis AJ</searchLink>; Department of Medicine, Whangarei Hospital, New Zealand (A.J.D.).<br /><searchLink fieldCode="AU" term="%22Wu+TY%22">Wu TY</searchLink>; Department of Neurology, Christchurch Hospital, New Zealand (T.Y.W.).<br /><searchLink fieldCode="AU" term="%22Kaesmacher+J%22">Kaesmacher J</searchLink>; University Institute of Diagnostic and Interventional Neuroradiology (J.K.), Inselspital, Bern University Hospital, University of Bern, Switzerland.; Diagnostic and Interventional Neuroradiology, Tours, France (J.K.).; Le Studium Loire Valley Institute for Advanced Studies, Orléans, France (J.K.).<br /><searchLink fieldCode="AU" term="%22Fischer+U%22">Fischer U</searchLink>; Department of Neurology, Stroke Research Center Bern (T.R.M., P.B., F.Z.-M., U.F., D.J.S.), Inselspital, Bern University Hospital, University of Bern, Switzerland.<br /><searchLink fieldCode="AU" term="%22Seiffge+DJ%22">Seiffge DJ</searchLink>; Department of Neurology, Stroke Research Center Bern (T.R.M., P.B., F.Z.-M., U.F., D.J.S.), Inselspital, Bern University Hospital, University of Bern, Switzerland.
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  Data: <searchLink fieldCode="JN" term="%220235266%22">Stroke</searchLink> [Stroke] 2025 Oct; Vol. 56 (10), pp. 2836-2845. <i>Date of Electronic Publication: </i>2025 Jul 22.
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  Data: Journal Article; Comparative Study; Multicenter Study
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Lippincott+Williams+%26+Wilkins%22">Lippincott Williams & Wilkins </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0235266 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1524-4628 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200392499%22">00392499 </searchLink><i>NLM ISO Abbreviation: </i>Stroke <i>Subsets: </i>MEDLINE
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        Value: 10.1161/STROKEAHA.125.051384
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      – Code: eng
        Text: English
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      – TitleFull: Intravenous Thrombolysis in Patients With Recent Intake of Direct Oral Anticoagulants: A Target Trial Analysis and Comparison With Reversal Agent Use.
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              Text: 2025 Oct
              Type: published
              Y: 2025
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              Value: 1524-4628
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