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Physiological Consequences of Breathing Effort According to the Mode of Ventilation during Acute Hypoxemic Respiratory Failure.

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Title: Physiological Consequences of Breathing Effort According to the Mode of Ventilation during Acute Hypoxemic Respiratory Failure.
Authors: Telias I; Division of Respirology and Critical Care Medicine, University Health Network and Sinai Health System, Toronto, Ontario, Canada.; Interdepartmental Division of Critical Care Medicine, Department of Medicine.; Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St. Michael's Hospital-Unity Health Toronto, Toronto, Ontario, Canada., Madorno M; Instituto Tecnológico de Buenos Aires, Buenos Aires, Argentina., Pham T; Université Paris-Saclay, Assistance Publique-Hôpitaux de Paris, Service de Médecine Intensive - Réanimation, Hôpital de Bicêtre, Départements Médicaux Universitaires Cœur-Rein-Réanimation-Vaisseaux-Explorations, Fédération Hospitalo-Universitaire SEPSIS, Groupe de Recherche Clinique CARMAS, Le Kremlin-Bicêtre, France.; Université Paris-Saclay, Université de Versailles Saint-Quentin-en-Yvelines, University Paris-Sud, Inserm U1018, Equipe d'Epidémiologie Respiratoire Intégrative, Centre de Recherche en Épidémiologie et Santé des Populations, Villejuif, France., Coudroy R; Médecine Intensive Réanimation, Centre Hospitalier Universitaire de Poitiers, Poitiers, France.; INSERM CIC 1402, Groupe IS-ALIVE Group de Recherche, Université de Poitiers, Poitiers, France., Mellado Artigas R; Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St. Michael's Hospital-Unity Health Toronto, Toronto, Ontario, Canada.; Unidad de Cuidados Intensivos Quirúrgicos, Hospital Clínic de Barcelona, Barcelona, España.; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain.; Institut d'Investigacions Biomèdiques August Pi I Sunyer, Barcelona, Spain., Baedorf-Kassis E; Division of Pulmonary and Critical Care Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts., Chen CW; National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan., Spadaro S; Department of Translational Medicine, Intensive Care Unit, University of Ferrara, Ferrara University Hospital, Ferrara, Italy., Chiumello D; Department of Health Sciences and.; Coordinated Research Center on Respiratory Failure, University of Milan, Milan, Italy.; Department of Anesthesia and Intensive Care, Azienda Socio Sanitaria Territoriale Santi Paolo e Carlo, San Paolo University Hospital Milan, Milan, Italy., Beitler J; Division of Pulmonary, Critical Care, and Sleep Medicine, Grossman School of Medicine, New York University, New York, New York., Kondili E; Department of Intensive Care Medicine, School of Medicine, University Hospital of Heraklion, University of Crete, Heraklion, Greece., Tiribelli N; Servicio de Kinesiología, Unidad de Medicina Crítica y Terapia Intensiva, Complejo Médico de la Policía Federal Argentina Churruca Visca, Buenos Aires, Argentina., Fredes S; Servicio de Kinesiología, Unidad de Medicina Crítica y Terapia Intensiva, Complejo Médico de la Policía Federal Argentina Churruca Visca, Buenos Aires, Argentina.; Sanatorio de la Trinidad Mitre, Buenos Aires, Argentina., Becher T; Department of Anesthesiology and Intensive Care Medicine, University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany., Dres M; Sorbonne Université, INSERM, UMRS 1158 Neurophysiologie Respiratoire Expérimentale et Clinique, Paris, France.; Sorbonne Université, Assistance Publique-Hôpitaux de Paris, Hôpital Pitié-Salpêtrière, Service de Médecine Intensive-Réanimation, Paris, France., Liu K; Institute of Health Policy, Management and Evaluation, and., Terzi N; Service de Médicine Intensive-Réanimation, Centre Hospitalier Universitaire Grenoble-Alpes, Grenoble, France.; University Grenoble Alps, Inserm U1042, HP2, Grenoble, France., Guérin C; Medical Intensive Care Unit, Edouard Herriot Teaching Hospital, Lyon, France.; University of Lyon, Lyon, France., Mauri T; Dipartimento di Anestesia, Rianimazione ed Emergenza-Urgenza, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Ca' Granda Ospedale Maggiore Policlinico, Università degli Studi di Milano, Milan, Italy., Roca O; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain.; Servei de Medicina Intensiva, Parc Taulí Hospital Universitari, Institut d'Investigació i Innovació Parc Taulí, Sabadell, Spain.; Departament de Medicina, Universitat Autònoma de Barcelona, Bellaterra, Spain., Mancebo J; Servei de Medicina Intensiva, Hospital de Sant Pau, Barcelona, Spain., Rodriguez N; Servei de Medicina Intensiva, Hospital de Sant Pau, Barcelona, Spain., Arnal JM; Service de Réanimation Polyvalente et Unité de Ventilation à Domicile, Hôpital Sainte Musse, Toulon, France., Goligher EC; Division of Respirology and Critical Care Medicine, University Health Network and Sinai Health System, Toronto, Ontario, Canada.; Interdepartmental Division of Critical Care Medicine, Department of Medicine.; Department of Physiology, University of Toronto, Toronto, Ontario, Canada.; Toronto General Hospital Research Institute, Toronto, Ontario, Canada., Diehl JL; University of Paris Cité, Inserm, Innovative Therapies in Haemostasis, Paris, France.; Service de Médecine Intensive Réanimation, Assistance Publique-Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Paris, France., Jochmans S; Service de Réanimation Polyvalente, Hôpital Marc Jacquet, Melun, France., Beloncle F; Medical ICU, University Hospital of Angers, Vent'Lab, University of Angers, Angers, France., Rittayamai N; Division of Respiratory Diseases and Tuberculosis, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand., Mojoli F; Anesthesia and Intensive Care 1St, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo, Rianimazione I, Pavia, Italy.; Department of Clinical-Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy., Heunks L; Department of Intensive Care Medicine, Radboud University Medical Center, Nijmegen, the Netherlands., de Vries H; Department of Critical Care Medicine, Amsterdam University Medical Center, Amsterdam, the Netherlands.; Amsterdam Cardiovascular Science Research Institute, Amsterdam, the Netherlands., Zhou JX; Department of Critical Care Medicine, Beijing Tiantan Hospital, Capital Medical University, Beijing, China; and., Guervilly C; Centre d'Etudes et de Recherches sur les Services de Santé et Qualité de Vie EA 3279, Médecine Intensive Réanimation, Hôpital Nord, Assistance Publique-Hôpitaux de Marseille, Marseille, France., Brochard L; Interdepartmental Division of Critical Care Medicine, Department of Medicine.; Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St. Michael's Hospital-Unity Health Toronto, Toronto, Ontario, Canada.
Corporate Authors: BEARDS and PLUG Investigators
Source: American journal of respiratory and critical care medicine [Am J Respir Crit Care Med] 2026 Mar 01; Vol. 212 (3), pp. 487-499.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: American Thoracic Society Country of Publication: England NLM ID: 9421642 Publication Model: Print Cited Medium: Internet ISSN: 1535-4970 (Electronic) Linking ISSN: 1073449X NLM ISO Abbreviation: Am J Respir Crit Care Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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Description
ISSN:1535-4970
DOI:10.1164/rccm.202411-2155OC