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Mitochondrial dysfunction drives basal cell hyperplasia in eosinophilic oesophagitis.

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Title: Mitochondrial dysfunction drives basal cell hyperplasia in eosinophilic oesophagitis.
Authors: Morimoto M; Columbia University Herbert Irving Comprehensive Cancer Center, New York, New York, USA., Kawasaki K; Columbia University Herbert Irving Comprehensive Cancer Center, New York, New York, USA., McNamee N; Massachusetts General Hospital, Boston, Massachusetts, USA., Flashner S; Columbia University Herbert Irving Comprehensive Cancer Center, New York, New York, USA., Shimonosono R; Columbia University Herbert Irving Comprehensive Cancer Center, New York, New York, USA., Shimonosono M; Columbia University Herbert Irving Comprehensive Cancer Center, New York, New York, USA., Matsuura N; Columbia University Herbert Irving Comprehensive Cancer Center, New York, New York, USA., Tomita Y; Columbia University Herbert Irving Comprehensive Cancer Center, New York, New York, USA., Hirose W; Columbia University Herbert Irving Comprehensive Cancer Center, New York, New York, USA., Teranishi R; Division of Gastroenterology, Hepatology, and Nutrition, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA., Itami T; Division of Gastroenterology, Hepatology, and Nutrition, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA., Guha M; Columbia University Herbert Irving Comprehensive Cancer Center, New York, New York, USA., Rajagopalan P; Massachusetts General Hospital, Boston, Massachusetts, USA., Martin C; Columbia University Herbert Irving Comprehensive Cancer Center, New York, New York, USA.; Division of Digestive & Liver Diseases, Department of Medicine, Columbia University, New York, New York, USA.; Digestive & Liver Disease Research Center, Columbia University, New York, New York, USA., Golden H; Division of Gastroenterology, Hepatology, and Nutrition, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA., Dhakal D; Division of Gastroenterology, Hepatology, and Nutrition, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA., Wilkins BJ; Department of Pathology and Laboratory Medicine, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA., Klein-Szanto AJ; Histopathology Facility, Fox Chase Cancer Center, Philadelphia, Pennsylvania, USA., Wangensteen KJ; Division of Gastroenterology and Hepatology, Department of Medicine, Mayo Clinic, Rochester, Minnesota, USA., Abrams JA; Columbia University Herbert Irving Comprehensive Cancer Center, New York, New York, USA.; Division of Digestive & Liver Diseases, Department of Medicine, Columbia University, New York, New York, USA.; Digestive & Liver Disease Research Center, Columbia University, New York, New York, USA., Pomenti S; Division of Digestive & Liver Diseases, Department of Medicine, Columbia University, New York, New York, USA., Katzka DA; Columbia University Herbert Irving Comprehensive Cancer Center, New York, New York, USA.; Division of Digestive & Liver Diseases, Department of Medicine, Columbia University, New York, New York, USA., Que J; Columbia University Herbert Irving Comprehensive Cancer Center, New York, New York, USA.; Division of Digestive & Liver Diseases, Department of Medicine, Columbia University, New York, New York, USA., Whelan KA; Fels Cancer Institute for Personalized Medicine, Department of Cancer & Cellular Biology, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, USA., Muir AB; Division of Gastroenterology, Hepatology, and Nutrition, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.; Pediatrics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA., Kita H; Division of Allergy, Asthma, and Clinical Immunology, Mayo Clinic Arizona, Scottsdale, Arizona, USA., Wright BL; Division of Allergy, Asthma, and Clinical Immunology, Mayo Clinic Arizona, Scottsdale, Arizona, USA., Doyle AD; Division of Allergy, Asthma, and Clinical Immunology, Mayo Clinic Arizona, Scottsdale, Arizona, USA., Nakagawa H; Columbia University Herbert Irving Comprehensive Cancer Center, New York, New York, USA uma.sachdeva@mgh.harvard.edu hn2360@cumc.columbia.edu.; Division of Digestive & Liver Diseases, Department of Medicine, Columbia University, New York, New York, USA.; Digestive & Liver Disease Research Center, Columbia University, New York, New York, USA., Sachdeva UM; Massachusetts General Hospital, Boston, Massachusetts, USA uma.sachdeva@mgh.harvard.edu hn2360@cumc.columbia.edu.; Thoracic Surgery, Massachusetts General Hospital, Boston, Massachusetts, USA.
Source: Gut [Gut] 2025 Sep 08; Vol. 74 (10), pp. 1571-1588. Date of Electronic Publication: 2025 Sep 08.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: British Medical Assn Country of Publication: England NLM ID: 2985108R Publication Model: Electronic Cited Medium: Internet ISSN: 1468-3288 (Electronic) Linking ISSN: 00175749 NLM ISO Abbreviation: Gut Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Mitochondrial dysfunction drives basal cell hyperplasia in eosinophilic oesophagitis.
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  Data: <searchLink fieldCode="AU" term="%22Morimoto+M%22">Morimoto M</searchLink>; Columbia University Herbert Irving Comprehensive Cancer Center, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Kawasaki+K%22">Kawasaki K</searchLink>; Columbia University Herbert Irving Comprehensive Cancer Center, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22McNamee+N%22">McNamee N</searchLink>; Massachusetts General Hospital, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Flashner+S%22">Flashner S</searchLink>; Columbia University Herbert Irving Comprehensive Cancer Center, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Shimonosono+R%22">Shimonosono R</searchLink>; Columbia University Herbert Irving Comprehensive Cancer Center, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Shimonosono+M%22">Shimonosono M</searchLink>; Columbia University Herbert Irving Comprehensive Cancer Center, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Matsuura+N%22">Matsuura N</searchLink>; Columbia University Herbert Irving Comprehensive Cancer Center, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Tomita+Y%22">Tomita Y</searchLink>; Columbia University Herbert Irving Comprehensive Cancer Center, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Hirose+W%22">Hirose W</searchLink>; Columbia University Herbert Irving Comprehensive Cancer Center, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Teranishi+R%22">Teranishi R</searchLink>; Division of Gastroenterology, Hepatology, and Nutrition, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Itami+T%22">Itami T</searchLink>; Division of Gastroenterology, Hepatology, and Nutrition, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Guha+M%22">Guha M</searchLink>; Columbia University Herbert Irving Comprehensive Cancer Center, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Rajagopalan+P%22">Rajagopalan P</searchLink>; 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Division of Digestive & Liver Diseases, Department of Medicine, Columbia University, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Que+J%22">Que J</searchLink>; Columbia University Herbert Irving Comprehensive Cancer Center, New York, New York, USA.; Division of Digestive & Liver Diseases, Department of Medicine, Columbia University, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Whelan+KA%22">Whelan KA</searchLink>; Fels Cancer Institute for Personalized Medicine, Department of Cancer & Cellular Biology, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Muir+AB%22">Muir AB</searchLink>; Division of Gastroenterology, Hepatology, and Nutrition, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.; Pediatrics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Kita+H%22">Kita H</searchLink>; Division of Allergy, Asthma, and Clinical Immunology, Mayo Clinic Arizona, Scottsdale, Arizona, USA.<br /><searchLink fieldCode="AU" term="%22Wright+BL%22">Wright BL</searchLink>; Division of Allergy, Asthma, and Clinical Immunology, Mayo Clinic Arizona, Scottsdale, Arizona, USA.<br /><searchLink fieldCode="AU" term="%22Doyle+AD%22">Doyle AD</searchLink>; Division of Allergy, Asthma, and Clinical Immunology, Mayo Clinic Arizona, Scottsdale, Arizona, USA.<br /><searchLink fieldCode="AU" term="%22Nakagawa+H%22">Nakagawa H</searchLink>; Columbia University Herbert Irving Comprehensive Cancer Center, New York, New York, USA uma.sachdeva@mgh.harvard.edu hn2360@cumc.columbia.edu.; Division of Digestive & Liver Diseases, Department of Medicine, Columbia University, New York, New York, USA.; Digestive & Liver Disease Research Center, Columbia University, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Sachdeva+UM%22">Sachdeva UM</searchLink>; Massachusetts General Hospital, Boston, Massachusetts, USA uma.sachdeva@mgh.harvard.edu hn2360@cumc.columbia.edu.; Thoracic Surgery, Massachusetts General Hospital, Boston, Massachusetts, USA.
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  Data: <searchLink fieldCode="JN" term="%222985108R%22">Gut</searchLink> [Gut] 2025 Sep 08; Vol. 74 (10), pp. 1571-1588. <i>Date of Electronic Publication: </i>2025 Sep 08.
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