Advancing In Vivo Detection of T-Cell Function: Development and Preclinical Evaluation of 89Zr-Ivuxolimab, a Human OX40 PET Tracer.
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| Title: | Advancing In Vivo Detection of T-Cell Function: Development and Preclinical Evaluation of 89Zr-Ivuxolimab, a Human OX40 PET Tracer. |
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| Authors: | Kalita M; Molecular Imaging Program at Stanford, Department of Radiology, Stanford University School of Medicine, Stanford, California.; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California., Kuo RC; Molecular Imaging Program at Stanford, Department of Radiology, Stanford University School of Medicine, Stanford, California.; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California., Reyes ST; Molecular Imaging Program at Stanford, Department of Radiology, Stanford University School of Medicine, Stanford, California., Colburg DRC; Department of Pathology, Stanford University School of Medicine, Stanford, California., Falk IN; Molecular Imaging Program at Stanford, Department of Radiology, Stanford University School of Medicine, Stanford, California.; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California., Anders D; Molecular Imaging Program at Stanford, Department of Radiology, Stanford University School of Medicine, Stanford, California., Vermesh O; Molecular Imaging Program at Stanford, Department of Radiology, Stanford University School of Medicine, Stanford, California., Hayee S; Molecular Imaging Program at Stanford, Department of Radiology, Stanford University School of Medicine, Stanford, California., Azevedo EC; Molecular Imaging Program at Stanford, Department of Radiology, Stanford University School of Medicine, Stanford, California., Nagy SC; Molecular Imaging Program at Stanford, Department of Radiology, Stanford University School of Medicine, Stanford, California.; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California., Deal EM; Molecular Imaging Program at Stanford, Department of Radiology, Stanford University School of Medicine, Stanford, California., Chen AAD; Molecular Imaging Program at Stanford, Department of Radiology, Stanford University School of Medicine, Stanford, California., Kong CS; Department of Pathology, Stanford University School of Medicine, Stanford, California., Simonetta F; Division of Hematology, Department of Oncology, Geneva University Hospitals, Geneva, Switzerland.; Translational Research Center for Oncohematology, Department of Medicine, Faculty of Medicine, University of Geneva, Geneva, Switzerland; and., Giddabasappa A; Worldwide Research, Development and Medicine, Pfizer Inc., New York, New York., Keliher EJ; Worldwide Research, Development and Medicine, Pfizer Inc., New York, New York., Bartlett DW; Worldwide Research, Development and Medicine, Pfizer Inc., New York, New York., Maresca KP; Worldwide Research, Development and Medicine, Pfizer Inc., New York, New York., James ML; Molecular Imaging Program at Stanford, Department of Radiology, Stanford University School of Medicine, Stanford, California; mljames@stanford.edu israt@stanford.edu.; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California., Alam IS; Molecular Imaging Program at Stanford, Department of Radiology, Stanford University School of Medicine, Stanford, California; mljames@stanford.edu israt@stanford.edu. |
| Source: | Journal of nuclear medicine : official publication, Society of Nuclear Medicine [J Nucl Med] 2025 Sep 02; Vol. 66 (9), pp. 1449-1457. Date of Electronic Publication: 2025 Sep 02. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: Society of Nuclear Medicine Country of Publication: United States NLM ID: 0217410 Publication Model: Electronic Cited Medium: Internet ISSN: 1535-5667 (Electronic) Linking ISSN: 01615505 NLM ISO Abbreviation: J Nucl Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1535-5667 |
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| DOI: | 10.2967/jnumed.125.269799 |