Fibroblasts activated by miRs-185-5p, miR-652-5p, and miR-1246 shape the tumor microenvironment in triple-negative breast cancer via PATZ1 downregulation.

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Title: Fibroblasts activated by miRs-185-5p, miR-652-5p, and miR-1246 shape the tumor microenvironment in triple-negative breast cancer via PATZ1 downregulation.
Authors: De Luca G; Institute of Endotypes in Oncology, Metabolism and Immunology 'G. Salvatore' (IEOMI), Consiglio Nazionale delle Ricerche (CNR), Naples, Italy., Petrillo G; Department of Molecular Medicine and Medical Biotechnology, 'Federico II' University of Naples, V. Tommaso de Amicis 95, Naples, 80131, Italy., Scognamiglio I; Department of Molecular Medicine and Medical Biotechnology, 'Federico II' University of Naples, V. Tommaso de Amicis 95, Naples, 80131, Italy., Pane K; IRCCS SYNLAB SDN, Naples, Italy., Cocca L; Department of Molecular Medicine and Medical Biotechnology, 'Federico II' University of Naples, V. Tommaso de Amicis 95, Naples, 80131, Italy., Roscigno G; Department of Molecular Medicine and Medical Biotechnology, 'Federico II' University of Naples, V. Tommaso de Amicis 95, Naples, 80131, Italy., Mascolo M; Department of Molecular Medicine and Medical Biotechnology, 'Federico II' University of Naples, V. Tommaso de Amicis 95, Naples, 80131, Italy., Pignataro C; Department of Molecular Medicine and Medical Biotechnology, 'Federico II' University of Naples, V. Tommaso de Amicis 95, Naples, 80131, Italy., Verde S; Department of Biomedicine and Prevention, University of Rome 'Tor Vergata', Rome, Italy.; AKA Biotech S.r.l, Napoli, Italy., Fraticelli A; Department of Biomedicine and Prevention, University of Rome 'Tor Vergata', Rome, Italy., Fiore D; Institute of Endotypes in Oncology, Metabolism and Immunology 'G. Salvatore' (IEOMI), Consiglio Nazionale delle Ricerche (CNR), Naples, Italy.; Department of Molecular Medicine and Medical Biotechnology, 'Federico II' University of Naples, V. Tommaso de Amicis 95, Naples, 80131, Italy., Affinito A; Department of Molecular Medicine and Medical Biotechnology, 'Federico II' University of Naples, V. Tommaso de Amicis 95, Naples, 80131, Italy.; AKA Biotech S.r.l, Napoli, Italy., Nuzzo S; IRCCS SYNLAB SDN, Naples, Italy., Minic Z; Department of Chemistry and Biomolecular Sciences and John L. Holmes Mass Spectrometry Facility, University of Ottawa, Ottawa, Canada., De Micco F; Mediterranea Cardiocentro, Napoli, Italy., Thomas G; Mediterranea Cardiocentro, Napoli, Italy., Franzese M; IRCCS SYNLAB SDN, Naples, Italy., Berezovski MV; Department of Chemistry and Biomolecular Sciences and John L. Holmes Mass Spectrometry Facility, University of Ottawa, Ottawa, Canada., Fedele M; Institute of Endotypes in Oncology, Metabolism and Immunology 'G. Salvatore' (IEOMI), Consiglio Nazionale delle Ricerche (CNR), Naples, Italy., Condorelli G; Institute of Endotypes in Oncology, Metabolism and Immunology 'G. Salvatore' (IEOMI), Consiglio Nazionale delle Ricerche (CNR), Naples, Italy. gecondor@unina.it.; Department of Molecular Medicine and Medical Biotechnology, 'Federico II' University of Naples, V. Tommaso de Amicis 95, Naples, 80131, Italy. gecondor@unina.it., Quintavalle C; Institute of Endotypes in Oncology, Metabolism and Immunology 'G. Salvatore' (IEOMI), Consiglio Nazionale delle Ricerche (CNR), Naples, Italy.
Source: Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2025 Jul 25; Vol. 82 (1), pp. 287. Date of Electronic Publication: 2025 Jul 25.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: Switzerland NLM ID: 9705402 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-9071 (Electronic) Linking ISSN: 1420682X NLM ISO Abbreviation: Cell Mol Life Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1420-9071
DOI:10.1007/s00018-025-05781-y