Prognostication and treatment predictions for estrogen receptor positive early-stage breast cancer: incorporating the 70-gene signature into the PREDICT prognostication model.

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Title: Prognostication and treatment predictions for estrogen receptor positive early-stage breast cancer: incorporating the 70-gene signature into the PREDICT prognostication model.
Authors: Engelhardt EG; Division of Molecular Pathology, Netherlands Cancer Institute, Amsterdam, the Netherlands; Division of Psychosocial Research and Epidemiology, Netherlands Cancer Institute, Amsterdam, the Netherlands., Binuya MAE; Division of Molecular Pathology, Netherlands Cancer Institute, Amsterdam, the Netherlands; Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, the Netherlands; Department of Clinical Genetics, Leiden University Medical Center, Leiden, the Netherlands., Pharoah PDP; Department of Computational Biomedicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Poncet C; European Organisation for Research and Treatment of Cancer Headquarters, Brussels, Belgium., Rutgers EJT; Department of Surgical Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands., Piccart M; Oncology Department, Institut Jules Bordet and l'Université Libre de Bruxelles (U.L.B.), Hôpital Universitaire de Bruxelles (HUB), Brussels, Belgium., Cardoso F; Breast Unit, Champalimaud Clinical Center, Champalimaud Foundation, Lisbon, Portugal., van 't Veer LJ; UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA, USA., Steyerberg EW; Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, the Netherlands., Linn SC; Division of Molecular Pathology, Netherlands Cancer Institute, Amsterdam, the Netherlands; Division of Medical Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands; Department of Pathology, University Medical Center Utrecht, Utrecht, the Netherlands., Schmidt MK; Division of Molecular Pathology, Netherlands Cancer Institute, Amsterdam, the Netherlands; Department of Clinical Genetics, Leiden University Medical Center, Leiden, the Netherlands. Electronic address: mk.schmidt@nki.nl.
Source: Breast (Edinburgh, Scotland) [Breast] 2025 Oct; Vol. 83, pp. 104542. Date of Electronic Publication: 2025 Jul 19.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9213011 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-3080 (Electronic) Linking ISSN: 09609776 NLM ISO Abbreviation: Breast Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1532-3080
DOI:10.1016/j.breast.2025.104542