Prognostication and treatment predictions for estrogen receptor positive early-stage breast cancer: incorporating the 70-gene signature into the PREDICT prognostication model.

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Title: Prognostication and treatment predictions for estrogen receptor positive early-stage breast cancer: incorporating the 70-gene signature into the PREDICT prognostication model.
Authors: Engelhardt EG; Division of Molecular Pathology, Netherlands Cancer Institute, Amsterdam, the Netherlands; Division of Psychosocial Research and Epidemiology, Netherlands Cancer Institute, Amsterdam, the Netherlands., Binuya MAE; Division of Molecular Pathology, Netherlands Cancer Institute, Amsterdam, the Netherlands; Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, the Netherlands; Department of Clinical Genetics, Leiden University Medical Center, Leiden, the Netherlands., Pharoah PDP; Department of Computational Biomedicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Poncet C; European Organisation for Research and Treatment of Cancer Headquarters, Brussels, Belgium., Rutgers EJT; Department of Surgical Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands., Piccart M; Oncology Department, Institut Jules Bordet and l'Université Libre de Bruxelles (U.L.B.), Hôpital Universitaire de Bruxelles (HUB), Brussels, Belgium., Cardoso F; Breast Unit, Champalimaud Clinical Center, Champalimaud Foundation, Lisbon, Portugal., van 't Veer LJ; UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA, USA., Steyerberg EW; Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, the Netherlands., Linn SC; Division of Molecular Pathology, Netherlands Cancer Institute, Amsterdam, the Netherlands; Division of Medical Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands; Department of Pathology, University Medical Center Utrecht, Utrecht, the Netherlands., Schmidt MK; Division of Molecular Pathology, Netherlands Cancer Institute, Amsterdam, the Netherlands; Department of Clinical Genetics, Leiden University Medical Center, Leiden, the Netherlands. Electronic address: mk.schmidt@nki.nl.
Source: Breast (Edinburgh, Scotland) [Breast] 2025 Oct; Vol. 83, pp. 104542. Date of Electronic Publication: 2025 Jul 19.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9213011 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-3080 (Electronic) Linking ISSN: 09609776 NLM ISO Abbreviation: Breast Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Prognostication and treatment predictions for estrogen receptor positive early-stage breast cancer: incorporating the 70-gene signature into the PREDICT prognostication model.
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  Data: <searchLink fieldCode="AU" term="%22Engelhardt+EG%22">Engelhardt EG</searchLink>; Division of Molecular Pathology, Netherlands Cancer Institute, Amsterdam, the Netherlands; Division of Psychosocial Research and Epidemiology, Netherlands Cancer Institute, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Binuya+MAE%22">Binuya MAE</searchLink>; Division of Molecular Pathology, Netherlands Cancer Institute, Amsterdam, the Netherlands; Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, the Netherlands; Department of Clinical Genetics, Leiden University Medical Center, Leiden, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Pharoah+PDP%22">Pharoah PDP</searchLink>; Department of Computational Biomedicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Poncet+C%22">Poncet C</searchLink>; European Organisation for Research and Treatment of Cancer Headquarters, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Rutgers+EJT%22">Rutgers EJT</searchLink>; Department of Surgical Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Piccart+M%22">Piccart M</searchLink>; Oncology Department, Institut Jules Bordet and l'Université Libre de Bruxelles (U.L.B.), Hôpital Universitaire de Bruxelles (HUB), Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Cardoso+F%22">Cardoso F</searchLink>; Breast Unit, Champalimaud Clinical Center, Champalimaud Foundation, Lisbon, Portugal.<br /><searchLink fieldCode="AU" term="%22van+'t+Veer+LJ%22">van 't Veer LJ</searchLink>; UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Steyerberg+EW%22">Steyerberg EW</searchLink>; Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Linn+SC%22">Linn SC</searchLink>; Division of Molecular Pathology, Netherlands Cancer Institute, Amsterdam, the Netherlands; Division of Medical Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands; Department of Pathology, University Medical Center Utrecht, Utrecht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Schmidt+MK%22">Schmidt MK</searchLink>; Division of Molecular Pathology, Netherlands Cancer Institute, Amsterdam, the Netherlands; Department of Clinical Genetics, Leiden University Medical Center, Leiden, the Netherlands. Electronic address: mk.schmidt@nki.nl.
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  Data: <searchLink fieldCode="JN" term="%229213011%22">Breast (Edinburgh, Scotland)</searchLink> [Breast] 2025 Oct; Vol. 83, pp. 104542. <i>Date of Electronic Publication: </i>2025 Jul 19.
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              Text: 2025 Oct
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