IL-33-primed NLRP3 inflammasome in basophils drives IL-1β production and initiates atopic dermatitis inflammation.
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| Title: | IL-33-primed NLRP3 inflammasome in basophils drives IL-1β production and initiates atopic dermatitis inflammation. |
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| Authors: | Gunji Y; Division of Inflammation Research, Center for Molecular Medicine, Jichi Medical University, Tochigi, Japan., Matsumura T; Division of Cardiovascular and Genetic Research, Center for Molecular Medicine, Jichi Medical University, Tochigi, Japan. matsut@jichi.ac.jp.; Division of Cardiovascular Medicine, Department of Medicine, Jichi Medical University, Tochigi, Japan. matsut@jichi.ac.jp., Karasawa T; Division of Inflammation Research, Center for Molecular Medicine, Jichi Medical University, Tochigi, Japan., Komada T; Division of Inflammation Research, Center for Molecular Medicine, Jichi Medical University, Tochigi, Japan., Baatarjav C; Division of Inflammation Research, Center for Molecular Medicine, Jichi Medical University, Tochigi, Japan., Komori S; Division of Inflammation Research, Center for Molecular Medicine, Jichi Medical University, Tochigi, Japan., Aizawa H; Division of Inflammation Research, Center for Molecular Medicine, Jichi Medical University, Tochigi, Japan., Mizushina Y; Division of Inflammation Research, Center for Molecular Medicine, Jichi Medical University, Tochigi, Japan., Tsuda H; Division of Cardiovascular and Genetic Research, Center for Molecular Medicine, Jichi Medical University, Tochigi, Japan., Miyake K; Institute of Integrated Research, Institute of Science Tokyo, Tokyo, Japan., Maruyama T; Laboratory of Microbiology and Immunology, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan., Ohmori T; Department of Biochemistry, Jichi Medical University, Tochigi, Japan., Karasuyama H; Institute of Integrated Research, Institute of Science Tokyo, Tokyo, Japan., Takahashi M; Division of Inflammation Research, Center for Molecular Medicine, Jichi Medical University, Tochigi, Japan. masafumi2@jichi.ac.jp. |
| Source: | Cell death discovery [Cell Death Discov] 2025 Jul 27; Vol. 11 (1), pp. 346. Date of Electronic Publication: 2025 Jul 27. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101665035 Publication Model: Electronic Cited Medium: Print ISSN: 2058-7716 (Print) Linking ISSN: 20587716 NLM ISO Abbreviation: Cell Death Discov Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2058-7716 |
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| DOI: | 10.1038/s41420-025-02630-6 |
