Large-scale RNA-Seq mining reveals ciclopirox olamine induces TDP-43 cryptic exons.
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| Title: | Large-scale RNA-Seq mining reveals ciclopirox olamine induces TDP-43 cryptic exons. |
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| Authors: | Sinha IR; Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Sandal PS; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Spence H; Institute of Medical Sciences, University of Aberdeen, Aberdeen, UK., Burns GD; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Biochemistry, Cellular and Molecular Biology Graduate Program, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Mallika AP; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Abbasinejad F; Scientific Software Engineering Center, Johns Hopkins University, Baltimore, MD, USA., Irwin KE; Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Medical Scientist Training Program, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Cruz ALF; Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Wang V; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Biochemistry and Molecular Biology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA., Marx SR; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; University of Florida College of Medicine, Gainesville, FL, USA., Rodríguez JL; Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Langmead B; Kavli Neuroscience Discovery Institute, Johns Hopkins University, Baltimore, MD, USA.; Department of Computer Science, Johns Hopkins University, Baltimore, MD, USA., Gregory JM; Institute of Medical Sciences, University of Aberdeen, Aberdeen, UK.; Department of Pathology, NHS Grampian Tissue Biorepository, Aberdeen, UK., Wong PC; Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Ling JP; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. jling@jhu.edu. |
| Source: | Nature communications [Nat Commun] 2025 Jul 25; Vol. 16 (1), pp. 6878. Date of Electronic Publication: 2025 Jul 25. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-025-62004-5 |
