Comparative Effectiveness Research Using Randomized Trials and Observational Studies: Validity and Feasibility Considerations.

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Title: Comparative Effectiveness Research Using Randomized Trials and Observational Studies: Validity and Feasibility Considerations.
Authors: Bikdeli B; Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States.; Thrombosis Research Group, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States.; YNHH/Yale Center for Outcomes Research and Evaluation (CORE), New Haven, Connecticut, United States., Ross JS; YNHH/Yale Center for Outcomes Research and Evaluation (CORE), New Haven, Connecticut, United States.; Section of General Internal Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, United States., Bukhari S; Department of Cardiology, Johns Hopkins University, Baltimore, Maryland, United States., Jeffery MM; Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, Minnesota, United States.; Division of Health Care Delivery Research, Mayo Clinic, Rochester, Minnesota, United States.; Department of Emergency Medicine, Mayo Clinic, Rochester, Minnesota, United States., Lip GYH; Liverpool Centre for Cardiovascular Science at University of Liverpool, Liverpool John Moores University and Liverpool Heart and Chest Hospital, Liverpool, United Kingdom.; Department of Clinical Medicine, Aalborg University, Aalborg, Denmark., You SC; Department of Biomedical Systems Informatics, Yonsei University College of Medicine, Seoul, Republic of Korea., Cohen DJ; Cardiovascular Research Foundation, New York, New York, United States.; St Francis Hospital and Heart Center, Roslyn, New York, United States., Januzzi JL Jr; Division of Cardiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States.; Baim Institute for Clinical Research, Boston, Massachusetts, United States., Wallach JD; Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia, United States.
Source: Thrombosis and haemostasis [Thromb Haemost] 2026 Apr; Vol. 126 (4), pp. 335-345. Date of Electronic Publication: 2025 Jul 24.
Publication Type: Journal Article; Review
Journal Info: Publisher: Thieme Country of Publication: Germany NLM ID: 7608063 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2567-689X (Electronic) Linking ISSN: 03406245 NLM ISO Abbreviation: Thromb Haemost Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2567-689X
DOI:10.1055/a-2664-7887