Rare germline variant in NFATC4 associated with familial CLL.

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Title: Rare germline variant in NFATC4 associated with familial CLL.
Authors: Itchaki G; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Bai H; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Tiao G; Cancer Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Improgo R; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Oppenheimer BE; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Kasar S; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Tesar B; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Fernandes SM; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Pochet N; Cancer Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Machado JH; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Thrash EM; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Freedman AS; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Getz G; Cancer Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Krantz Family Center for Cancer Research and Dept. of Pathology, Massachusetts General Hospital, Boston, MA, USA.; Department of Pathology, Harvard Medical School, Boston, MA, USA., Brown JR; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA. Jennifer_Brown@dfci.harvard.edu.; Department of Medicine, Harvard Medical School, Boston, MA, USA. Jennifer_Brown@dfci.harvard.edu.
Source: Leukemia [Leukemia] 2025 Oct; Vol. 39 (10), pp. 2547-2550. Date of Electronic Publication: 2025 Jul 28.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5551 (Electronic) Linking ISSN: 08876924 NLM ISO Abbreviation: Leukemia Subsets: MEDLINE; In Process
Database: MEDLINE Ultimate
Description
ISSN:1476-5551
DOI:10.1038/s41375-025-02713-4