Novel Benzenesulfonamide Derivatives of 5'-Aminospirotriazolotriazine Exhibit Anti-Inflammatory Activity by Suppressing Pro-Inflammatory Mediators: In Vitro and In Vivo Evaluation Using a Rat Model of Carrageenan-Induced Paw Edema.
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| Title: | Novel Benzenesulfonamide Derivatives of 5'-Aminospirotriazolotriazine Exhibit Anti-Inflammatory Activity by Suppressing Pro-Inflammatory Mediators: In Vitro and In Vivo Evaluation Using a Rat Model of Carrageenan-Induced Paw Edema. |
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| Authors: | Hamed AM; Chemistry Department, Faculty of Science, Sohag University, Sohag 82524, Egypt., Enaili SS; Pharmaceutical Chemistry Department, Faculty of Pharmacy, University of Zawia, Al Zawia 16418, Libya., I Mohammed W; Department of Clinical Pharmacology, Faculty of Medicine, Sohag University, Sohag 82524, Egypt., Abouelella AMA; Department of Clinical Pharmacology, Faculty of Medicine, Sohag University, Sohag 82524, Egypt., Mohana ZEE; College of Medicine, Alexandria University, Alexandria 26571, Egypt., Monir DM; Physiology Department, Faculty of Medicine, Sohag University, Sohag 82524, Egypt., Soliman SS; Department of Zoology, Faculty of Science, Minia University, Minya 61519, Egypt., Hamouda EEM; Department of Pathology, College of Veterinary Medicine, Alexandria University, Alexandria 26571, Egypt., Elatif HMA; Department of Clinical Pharmacology, Faculty of Medicine, Sohag University, Sohag 82524, Egypt.; Department of Basic Medical Science, Al Rayan National College of Medicine, Madinah 41411, Saudi Arabia., El-Saghier AM; Chemistry Department, Faculty of Science, Sohag University, Sohag 82524, Egypt. |
| Source: | Biomedicines [Biomedicines] 2025 Jul 15; Vol. 13 (7). Date of Electronic Publication: 2025 Jul 15. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101691304 Publication Model: Electronic Cited Medium: Print ISSN: 2227-9059 (Print) Linking ISSN: 22279059 NLM ISO Abbreviation: Biomedicines Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2227-9059 |
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| DOI: | 10.3390/biomedicines13071732 |