CD248 induces PD-L1 expression on cancer-associated fibroblasts to promote NSCLC immune escape.

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Title: CD248 induces PD-L1 expression on cancer-associated fibroblasts to promote NSCLC immune escape.
Authors: Yang Z; Department of Immunology, Guizhou Medical University, Guiyang, China., Wang X; Department of Immunology, Guizhou Medical University, Guiyang, China., Zhu X; Department of Immunology, Guizhou Medical University, Guiyang, China.; Department of Thoracic Surgery, The Affiliated Hospital of Guizhou Medical University, Guiyang, China., Li L; Department of Immunology, Guizhou Medical University, Guiyang, China.; Department of Thoracic Surgery, The Affiliated Hospital of Guizhou Medical University, Guiyang, China., Zeng X; Department of Immunology, Guizhou Medical University, Guiyang, China., Ren J; Department of Immunology, Guizhou Medical University, Guiyang, China.; School of Public Health, The Key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education, Guizhou Medical University, Guiyang, China., Wang L; Department of Immunology, Guizhou Medical University, Guiyang, China., Wu J; Department of Immunology, Guizhou Medical University, Guiyang, China., Zhang Q; Department of Immunology, Guizhou Medical University, Guiyang, China., Wang S; Department of Immunology, Guizhou Medical University, Guiyang, China., Lu M; Department of Immunology, Guizhou Medical University, Guiyang, China., Zhai J; Department of Immunology, Guizhou Medical University, Guiyang, China., Liu X; Guizhou Prenatal Diagnsis Center, The Affiliated Hospital of Guizhou Medical University, Guiyang, China., Xiao J; Department of Immunology, Guizhou Medical University, Guiyang, China., Jin T; Department of Immunology, Guizhou Medical University, Guiyang, China., Zhang Y; Department of Immunology, Guizhou Medical University, Guiyang, China., Wang Y; School of Public Health, The Key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education, Guizhou Medical University, Guiyang, China.; Guizhou Key Laboratory of Microbio and Infectious Disease Prevention and Control, School of Basic Medical Sciences, Guizhou Medical University, Guiyang, China., Zhang J; Department of Thoracic Surgery, The Affiliated Hospital of Guizhou Medical University, Guiyang, China., Zeng Z; Department of Immunology, Guizhou Medical University, Guiyang, China.; Guizhou Key Laboratory of Microbio and Infectious Disease Prevention and Control, School of Basic Medical Sciences, Guizhou Medical University, Guiyang, China.; Immune Cells and Antibody Engineering Research Center of Guizhou Province, Key Laboratory of Biology and Medical Engineering, Guizhou Medical University, Guiyang, China., Wu J; Department of Immunology, Guizhou Medical University, Guiyang, China.; Guizhou Key Laboratory of Microbio and Infectious Disease Prevention and Control, School of Basic Medical Sciences, Guizhou Medical University, Guiyang, China.; Immune Cells and Antibody Engineering Research Center of Guizhou Province, Key Laboratory of Biology and Medical Engineering, Guizhou Medical University, Guiyang, China.; The State Key Laboratory of Cancer Biology, Department of Biochemistry and Molecular Biology, The Fourth Military Medical University, Xi'an, China.; Tumor Immunotherapy Technology Engineering Research Center of Guizhou Medical University, Guizhou Medical University, Guiyang, China.
Source: Frontiers in cell and developmental biology [Front Cell Dev Biol] 2025 Jul 15; Vol. 13, pp. 1635915. Date of Electronic Publication: 2025 Jul 15 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media S.A Country of Publication: Switzerland NLM ID: 101630250 Publication Model: eCollection Cited Medium: Print ISSN: 2296-634X (Print) Linking ISSN: 2296634X NLM ISO Abbreviation: Front Cell Dev Biol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:2296-634X
DOI:10.3389/fcell.2025.1635915