Critical analysis of translational potential of rodent models of white matter pathology across a wide spectrum of human diseases.

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Title: Critical analysis of translational potential of rodent models of white matter pathology across a wide spectrum of human diseases.
Authors: Zhou W; Department of Histology and Embryology, Third Military Medical University, Chongqing, 400038, China., Xia S; Department of Histology and Embryology, Third Military Medical University, Chongqing, 400038, China., Wang C; Department of Histology and Embryology, Third Military Medical University, Chongqing, 400038, China.; Research Centre, Seventh Affiliated Hospital of Sun Yat-sen University, Shenzhen, 518107, China., Yang Q; Department of Neurology, Second Affiliated Hospital, Chongqing Institute for Brain and Intelligence, Third Military Medical University, Chongqing, 400037, China., Verkhratsky A; Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, M139PL, UK. Alexej.Verkhratsky@manchester.ac.uk.; Department of Neurosciences, University of the Basque Country, CIBERNED, Leioa 48940, and IKERBASQUE Basque Foundation for Science, Bilbao, Spain. Alexej.Verkhratsky@manchester.ac.uk.; International Collaborative Center on Big Science Plan for Purinergic Signalling, Chengdu University of Traditional Chinese Medicine, Chengdu, China. Alexej.Verkhratsky@manchester.ac.uk.; Celica Biomedical, Tehnološki park 24, 1000, Ljubljana, Slovenia. Alexej.Verkhratsky@manchester.ac.uk.; Department of Forensic Analytical Toxicology, School of Forensic Medicine, China Medical University, Shenyang, 110122, China. Alexej.Verkhratsky@manchester.ac.uk., Niu J; Department of Histology and Embryology, Third Military Medical University, Chongqing, 400038, China. jianqinniu@163.com.; Chongqing Key Laboratory of Neurobiology, Chongqing, 400038, China. jianqinniu@163.com.; Key Laboratory of Major Brain Disease and Aging Research, Chongqing Medical University, Chongqing, 400016, China. jianqinniu@163.com.; State Key Laboratory of Trauma and Chemical Poisoning, Chongqing, 400042, China. jianqinniu@163.com.
Source: Cell death & disease [Cell Death Dis] 2025 Jul 31; Vol. 16 (1), pp. 580. Date of Electronic Publication: 2025 Jul 31.
Publication Type: Journal Article; Review
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-4889
DOI:10.1038/s41419-025-07893-6