Impact on the Leishmania mexicana transcriptome due to knockout of genes encoding orthologs of methyltransferases involved in m1A and m5C mRNA modifications.

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Title: Impact on the Leishmania mexicana transcriptome due to knockout of genes encoding orthologs of methyltransferases involved in m1A and m5C mRNA modifications.
Authors: Bezerra AM; Department of Microbiology, Aggeu Magalhães Institute, Fiocruz Pernambuco, Recife, PE, Brazil., Leite AB; Department of Microbiology, Immunology and Parasitology, UNIFESP, São Paulo, SP, Brazil., de Souza Reis CR; Department of Microbiology, Aggeu Magalhães Institute, Fiocruz Pernambuco, Recife, PE, Brazil.; Institute of Biological Sciences, University of Pernambuco (ICB/UPE), Recife, PE, Brazil., de Lemos Padilha Pitta JL; Department of Microbiology, Aggeu Magalhães Institute, Fiocruz Pernambuco, Recife, PE, Brazil., Maran SR; Department of Microbiology, Immunology and Parasitology, UNIFESP, São Paulo, SP, Brazil., Moretti NS; Department of Microbiology, Immunology and Parasitology, UNIFESP, São Paulo, SP, Brazil.; Department of Pathology and Microbiology, Faculty of Veterinary Medicine, Université de Montréal, Saint-Hyacinthe, Canada.; The Research Group on Infectious Diseases in Production Animals (GREMIP), Faculty of Veterinary Medicine, University of Montreal, Saint-Hyacinthe, Canada., Moura DMN; Department of Immunology, Aggeu Magalhães Institute, Fiocruz Pernambuco, Recife, PE, Brazil. danielle.moura@fiocruz.br., Rezende AM; Department of Microbiology, Aggeu Magalhães Institute, Fiocruz Pernambuco, Recife, PE, Brazil. antonio.rezende@fiocruz.br.; Research Group of Biotechnology Applied to Pathogens, René Rachou Institute, Fiocruz Minas Gerais, Belo Horizonte, MG, Brazil. antonio.rezende@fiocruz.br.
Source: Parasites & vectors [Parasit Vectors] 2025 Jul 31; Vol. 18 (1), pp. 315. Date of Electronic Publication: 2025 Jul 31.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101462774 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-3305 (Electronic) Linking ISSN: 17563305 NLM ISO Abbreviation: Parasit Vectors Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1756-3305
DOI:10.1186/s13071-025-06969-8