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A multicentric national phase II trial assessing TIslelizumab in monotherapy for patients with Hepatocellular Carcinoma Child-Pugh B and ALBI grade 1 or 2 liver function score: The UCGI 41 HESTIA TRIAL DESIGN AND PRELIMINARY SAFETY Data.

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Title: A multicentric national phase II trial assessing TIslelizumab in monotherapy for patients with Hepatocellular Carcinoma Child-Pugh B and ALBI grade 1 or 2 liver function score: The UCGI 41 HESTIA TRIAL DESIGN AND PRELIMINARY SAFETY Data.
Authors: Bourien H; Medical Oncologist, GastroIntestinal Cancer - Centre Eugène Marquis France. Electronic address: h.bourien@rennes.unicancer.fr., Adhoute X; Medical Oncologist, GastroIntestinal Cancer- Hôpital Saint Joseph Marseille France., Campillo-Gimenez B; Biostatistic, Centre Eugènes Marquis, Rennes, France., Bouattour M; Medical Oncologist, GastroIntestinal Cancer, CHU Beaujon, Clichy, France., Assenat E; Medical Oncologist, GastroIntestinal Cancer, CHU Montpellier, France., Nahon P; Medical Oncologist, GastroIntestinal Cancer, Hôpital Avicenne, Bobigny, France., Launay S; Medical Oncologist, GastroIntestinal Cancer, Institut Paoli Calmette, Marseille, France., Oberti F; Medical Oncologist, GastroIntestinal Cancer, CHU d'Angers, France., Saviano A; Medical Oncologist, GastroIntestinal Cancer, CHRU de Strasbourg, France., Decaens T; Medical Oncologist, Université de Grenoble Alpes/Hepato-Gastroenterology and Digestive Oncology Department, CHU Grenoble Alpes/Institute for Advanced Biosciences, CNRS UMR 5309-INSERM U1209, 38043 Grenoble, France., Merle P; Medical Oncologist, GastroIntestinal Cancer, Hôpital de la Croix Rousse, Lyon, France., Harlé A; Biopathology Department, Institut de Cancérologie de Lorraine, CNRS UMR 7039 CRAN, Université de Lorraine, France., Lecomte T; Medical Oncologist, GastroIntestinal Cancer, CHRU de Tours, Tours, France., Ternant D; Centre Pilote de suivi Biologique des traitements par Anticorps, CHRU de Tours, France., Monard L; UNICANCER R&D, 101 rue de Tolbiac 75013 Paris France., Pezzella V; Medical Oncologist, GastroIntestinal Cancer, Hôpital Haut Lévêque, Bordeaux, France., Blanc JF; Medical Oncologist, GastroIntestinal Cancer, Hôpital Haut Lévêque, Bordeaux, France., Edeline J; Medical Oncologist, GastroIntestinal Cancer - Centre Eugène Marquis France.
Source: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver [Dig Liver Dis] 2025 Oct; Vol. 57 (10), pp. 2011-2015. Date of Electronic Publication: 2025 Aug 05.
Publication Type: Journal Article; Clinical Trial Protocol
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 100958385 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-3562 (Electronic) Linking ISSN: 15908658 NLM ISO Abbreviation: Dig Liver Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1878-3562
DOI:10.1016/j.dld.2025.07.019