Effects of realgar-indigo naturalis formula on a zebrafish tumor xenograft model induced by human acute promyelocytic leukemia cells: antitumor activity, hepatotoxicity, and transcriptomic analysis.

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Title: Effects of realgar-indigo naturalis formula on a zebrafish tumor xenograft model induced by human acute promyelocytic leukemia cells: antitumor activity, hepatotoxicity, and transcriptomic analysis.
Authors: Bai D; Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China., Zhang Z; Department of Biochemistry and Molecular and Cellular Biology, Georgetown University, Washington, DC, United States., Gao J; Teachers College, Columbia University, New York, NY, United States., Wang Q; Department of Biochemistry and Molecular and Cellular Biology, Georgetown University, Washington, DC, United States., Macdonald R; Department of Statistics, George Mason University, Fairfax, VA, United States., Xu Z; Department of Nursing, The University of Melbourne, Melbourne, VIC, Australia., Chen S; Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing, China., Huang N; Department of Biochemistry and Molecular and Cellular Biology, Georgetown University, Washington, DC, United States., Luo L; Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.; Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, TX, United States.
Source: Frontiers in pharmacology [Front Pharmacol] 2025 Jul 18; Vol. 16, pp. 1619352. Date of Electronic Publication: 2025 Jul 18 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media] Country of Publication: Switzerland NLM ID: 101548923 Publication Model: eCollection Cited Medium: Print ISSN: 1663-9812 (Print) Linking ISSN: 16639812 NLM ISO Abbreviation: Front Pharmacol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:1663-9812
DOI:10.3389/fphar.2025.1619352