Fasting is required for many of the benefits of calorie restriction in the 3xTg mouse model of Alzheimer's disease.
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| Title: | Fasting is required for many of the benefits of calorie restriction in the 3xTg mouse model of Alzheimer's disease. |
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| Authors: | Babygirija R; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA.; William S. Middleton Memorial Veterans Hospital, Madison, WI, USA.; Cellular and Molecular Biology Graduate Program, University of Wisconsin-Madison, Madison, WI, USA., Han JH; Cellular and Molecular Biology Graduate Program, University of Wisconsin-Madison, Madison, WI, USA., Sonsalla MM; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA.; William S. Middleton Memorial Veterans Hospital, Madison, WI, USA.; Comparative Biomedical Sciences Graduate Program, University of Wisconsin-Madison, Madison, WI, USA., Matoska R; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA.; William S. Middleton Memorial Veterans Hospital, Madison, WI, USA., Calubag MF; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA.; William S. Middleton Memorial Veterans Hospital, Madison, WI, USA.; Cellular and Molecular Biology Graduate Program, University of Wisconsin-Madison, Madison, WI, USA., Green CL; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA.; William S. Middleton Memorial Veterans Hospital, Madison, WI, USA., Tobon A; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA.; William S. Middleton Memorial Veterans Hospital, Madison, WI, USA., Yeh CY; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA.; William S. Middleton Memorial Veterans Hospital, Madison, WI, USA., Vertein D; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA., Schlorf S; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA.; William S. Middleton Memorial Veterans Hospital, Madison, WI, USA., Illiano J; William S. Middleton Memorial Veterans Hospital, Madison, WI, USA.; Wisconsin Surgical Laboratory in Metabolism, Department of Surgery, University of Wisconsin-Madison, Madison, WI, USA., Liu Y; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA.; William S. Middleton Memorial Veterans Hospital, Madison, WI, USA.; Endocrinology and Reproductive Physiology Graduate Program, University of Wisconsin-Madison, Madison, WI, USA., Grunow I; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA.; William S. Middleton Memorial Veterans Hospital, Madison, WI, USA., Rigby MJ; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA.; Waisman Center, University of Wisconsin-Madison, Madison, WI, USA.; Neuroscience Training Program, University of Wisconsin-Madison, Madison, WI, USA., Puglielli L; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA.; Waisman Center, University of Wisconsin-Madison, Madison, WI, USA.; Wisconsin Nathan Shock Center of Excellence in the Basic Biology of Aging, Madison, WI, USA., Harris DA; William S. Middleton Memorial Veterans Hospital, Madison, WI, USA.; Wisconsin Surgical Laboratory in Metabolism, Department of Surgery, University of Wisconsin-Madison, Madison, WI, USA.; University of Wisconsin Comprehensive Diabetes Center, Madison, WI, USA.; Wisconsin Nathan Shock Center of Excellence in the Basic Biology of Aging, Madison, WI, USA., Denu JM; Department of Biomolecular Chemistry, University of Wisconsin-Madison, Madison, WI, USA.; Wisconsin Nathan Shock Center of Excellence in the Basic Biology of Aging, Madison, WI, USA., Lamming DW; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA. dlamming@medicine.wisc.edu.; William S. Middleton Memorial Veterans Hospital, Madison, WI, USA. dlamming@medicine.wisc.edu.; Cellular and Molecular Biology Graduate Program, University of Wisconsin-Madison, Madison, WI, USA. dlamming@medicine.wisc.edu.; Comparative Biomedical Sciences Graduate Program, University of Wisconsin-Madison, Madison, WI, USA. dlamming@medicine.wisc.edu.; Endocrinology and Reproductive Physiology Graduate Program, University of Wisconsin-Madison, Madison, WI, USA. dlamming@medicine.wisc.edu.; University of Wisconsin Comprehensive Diabetes Center, Madison, WI, USA. dlamming@medicine.wisc.edu.; Wisconsin Nathan Shock Center of Excellence in the Basic Biology of Aging, Madison, WI, USA. dlamming@medicine.wisc.edu.; University of Wisconsin Carbone Cancer Center, Madison, WI, USA. dlamming@medicine.wisc.edu. |
| Source: | Nature communications [Nat Commun] 2025 Aug 04; Vol. 16 (1), pp. 7147. Date of Electronic Publication: 2025 Aug 04. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-025-62416-3 |
