Combining mucosal microbiome and host multi-omics data shows prognostic potential in paediatric ulcerative colitis.

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Title: Combining mucosal microbiome and host multi-omics data shows prognostic potential in paediatric ulcerative colitis.
Authors: Kulecka M; APC Microbiome Ireland, University College Cork, Cork, Ireland.; School of Microbiology, University College Cork, Cork, Ireland., O'Sullivan J; APC Microbiome Ireland, University College Cork, Cork, Ireland.; School of Microbiology, University College Cork, Cork, Ireland.; Research Ireland Centre for Research Training in Genomics Data Science, University of Galway, Galway, Ireland., Fitzgerald R; APC Microbiome Ireland, University College Cork, Cork, Ireland.; School of Microbiology, University College Cork, Cork, Ireland., Velikonja A; APC Microbiome Ireland, University College Cork, Cork, Ireland.; School of Microbiology, University College Cork, Cork, Ireland., Huseyin CE; APC Microbiome Ireland, University College Cork, Cork, Ireland.; School of Microbiology, University College Cork, Cork, Ireland., Laserna-Mendieta EJ; APC Microbiome Ireland, University College Cork, Cork, Ireland.; School of Microbiology, University College Cork, Cork, Ireland., Ruiz-Limón P; APC Microbiome Ireland, University College Cork, Cork, Ireland.; Department of Endocrinology and Nutrition, Virgen de la Victoria University Hospital, The Biomedical Research Institute of Malaga and Platform in Nanomedicine, Malaga, Spain., Eckenberger J; APC Microbiome Ireland, University College Cork, Cork, Ireland.; College of Health and Medicine, University College Cork, Cork, Ireland., Vidal-Marín M; APC Microbiome Ireland, University College Cork, Cork, Ireland., Truppel BA; APC Microbiome Ireland, University College Cork, Cork, Ireland., Singh R; APC Microbiome Ireland, University College Cork, Cork, Ireland., Naik S; Paediatric Gastroenterology, Barts Health NHS Trust, London, UK., Croft NM; Centre for Immunobiology, Blizard Institute, Queen Mary University of London, London, UK., Temko A; Department of Electrical and Electronic Engineering, University College Cork, Cork, Ireland., Zomer A; Department of Biomolecular Health Sciences (Infectious Diseases and Immunology), Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands., MacSharry J; APC Microbiome Ireland, University College Cork, Cork, Ireland.; School of Microbiology, University College Cork, Cork, Ireland., Melgar S; APC Microbiome Ireland, University College Cork, Cork, Ireland., Deb P; Paediatric Gastroenterology, Barts Health NHS Trust, London, UK., Sanderson IR; Centre for Immunobiology, Blizard Institute, Queen Mary University of London, London, UK., Claesson MJ; APC Microbiome Ireland, University College Cork, Cork, Ireland. M.Claesson@ucc.ie.; School of Microbiology, University College Cork, Cork, Ireland. M.Claesson@ucc.ie.
Source: Nature communications [Nat Commun] 2025 Aug 04; Vol. 16 (1), pp. 7157. Date of Electronic Publication: 2025 Aug 04.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-025-62533-z