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Adjuvant nivolumab in muscle-invasive urothelial carcinoma: exploratory biomarker analysis of the randomized phase 3 CheckMate 274 trial.

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Title: Adjuvant nivolumab in muscle-invasive urothelial carcinoma: exploratory biomarker analysis of the randomized phase 3 CheckMate 274 trial.
Authors: Galsky MD; Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA. matthew.galsky@mssm.edu., Bajorin DF; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Tomita Y; Department of Urology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan., Ye D; Department of Urology, Fudan University Shanghai Cancer Center, Shanghai, China., Agerbaek M; Department of Oncology, Aarhus University Hospital, Aarhus, Denmark., Enting D; Department of Oncology, Guy's and St Thomas' NHS Foundation Trust, London, UK., Peer A; Department of Oncology, Rambam Health Care Campus, Haifa, Israel., Milowsky M; Department of Medicine, University of North Carolina School of Medicine, Chapel Hill, NC, USA., Kobayashi K; Department of Urology, Sapporo Medical University, Sapporo, Japan., Grimm MO; Department of Urology, Jena University Hospital, Jena, Germany., Stenner F; Department of Oncology, University Hospital Basel, Basel, Switzerland., David JM; Translational Medicine, Bristol Myers Squibb, Princeton, NJ, USA.; Translational Sciences Oncology, BioNTech US, Cambridge, MA, USA., Li J; Translational Bioinformatics, Bristol Myers Squibb, Princeton, NJ, USA., Chasalow SD; Translational Bioinformatics, Bristol Myers Squibb, Princeton, NJ, USA.; Statistics, Metrum Research Group, Boston, MA, USA., Nasroulah F; Department of Clinical Research, Bristol Myers Squibb, Princeton, NJ, USA.; Daiichi Sankyo Inc, Basking Ridge, NJ, USA., Apfel A; Translational Bioinformatics, Bristol Myers Squibb, Princeton, NJ, USA.; Eisai Inc, Nutley, NJ, USA., Ünsal-Kaçmaz K; Translational Medicine, Bristol Myers Squibb, Princeton, NJ, USA.; Translational Sciences Oncology, BioNTech US, Cambridge, MA, USA., Necchi A; Department of Medical Oncology, IRCCS Ospedale San Raffaele, Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy.
Source: Nature medicine [Nat Med] 2025 Sep; Vol. 31 (9), pp. 3062-3073. Date of Electronic Publication: 2025 Aug 07.
Publication Type: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase III
Journal Info: Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-170X (Electronic) Linking ISSN: 10788956 NLM ISO Abbreviation: Nat Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Adjuvant nivolumab in muscle-invasive urothelial carcinoma: exploratory biomarker analysis of the randomized phase 3 CheckMate 274 trial.
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  Data: <searchLink fieldCode="AU" term="%22Galsky+MD%22">Galsky MD</searchLink>; Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA. matthew.galsky@mssm.edu.<br /><searchLink fieldCode="AU" term="%22Bajorin+DF%22">Bajorin DF</searchLink>; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Tomita+Y%22">Tomita Y</searchLink>; Department of Urology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.<br /><searchLink fieldCode="AU" term="%22Ye+D%22">Ye D</searchLink>; Department of Urology, Fudan University Shanghai Cancer Center, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Agerbaek+M%22">Agerbaek M</searchLink>; Department of Oncology, Aarhus University Hospital, Aarhus, Denmark.<br /><searchLink fieldCode="AU" term="%22Enting+D%22">Enting D</searchLink>; Department of Oncology, Guy's and St Thomas' NHS Foundation Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Peer+A%22">Peer A</searchLink>; Department of Oncology, Rambam Health Care Campus, Haifa, Israel.<br /><searchLink fieldCode="AU" term="%22Milowsky+M%22">Milowsky M</searchLink>; Department of Medicine, University of North Carolina School of Medicine, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Kobayashi+K%22">Kobayashi K</searchLink>; Department of Urology, Sapporo Medical University, Sapporo, Japan.<br /><searchLink fieldCode="AU" term="%22Grimm+MO%22">Grimm MO</searchLink>; Department of Urology, Jena University Hospital, Jena, Germany.<br /><searchLink fieldCode="AU" term="%22Stenner+F%22">Stenner F</searchLink>; Department of Oncology, University Hospital Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22David+JM%22">David JM</searchLink>; Translational Medicine, Bristol Myers Squibb, Princeton, NJ, USA.; Translational Sciences Oncology, BioNTech US, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Li+J%22">Li J</searchLink>; Translational Bioinformatics, Bristol Myers Squibb, Princeton, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Chasalow+SD%22">Chasalow SD</searchLink>; Translational Bioinformatics, Bristol Myers Squibb, Princeton, NJ, USA.; Statistics, Metrum Research Group, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Nasroulah+F%22">Nasroulah F</searchLink>; Department of Clinical Research, Bristol Myers Squibb, Princeton, NJ, USA.; Daiichi Sankyo Inc, Basking Ridge, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Apfel+A%22">Apfel A</searchLink>; Translational Bioinformatics, Bristol Myers Squibb, Princeton, NJ, USA.; Eisai Inc, Nutley, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Ünsal-Kaçmaz+K%22">Ünsal-Kaçmaz K</searchLink>; Translational Medicine, Bristol Myers Squibb, Princeton, NJ, USA.; Translational Sciences Oncology, BioNTech US, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Necchi+A%22">Necchi A</searchLink>; Department of Medical Oncology, IRCCS Ospedale San Raffaele, Milan, Italy.; Vita-Salute San Raffaele University, Milan, Italy.
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  Data: <searchLink fieldCode="JN" term="%229502015%22">Nature medicine</searchLink> [Nat Med] 2025 Sep; Vol. 31 (9), pp. 3062-3073. <i>Date of Electronic Publication: </i>2025 Aug 07.
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