Hybrid Cannabis sativa L. inflorescences exert an anti-inflammatory effect through the modulation of MAPK/NF-κB/NLRP3 inflammasome and JAK1/STAT6 pathway in HaCaT cells.

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Title: Hybrid Cannabis sativa L. inflorescences exert an anti-inflammatory effect through the modulation of MAPK/NF-κB/NLRP3 inflammasome and JAK1/STAT6 pathway in HaCaT cells.
Authors: Han JY; Department of Oriental Pharmacy, College of Pharmacy, Wonkwang University, Iksan, Republic of Korea.; Wonkwang-Oriental Medicines Research Institute, Wonkwang University, Iksan, Republic of Korea., Lim DW; Department of Oriental Pharmacy, College of Pharmacy, Wonkwang University, Iksan, Republic of Korea.; Wonkwang-Oriental Medicines Research Institute, Wonkwang University, Iksan, Republic of Korea., Kwon O; Department of Oriental Pharmacy, College of Pharmacy, Wonkwang University, Iksan, Republic of Korea.; Wonkwang-Oriental Medicines Research Institute, Wonkwang University, Iksan, Republic of Korea., Lee YJ; Department of Oriental Pharmacy, College of Pharmacy, Wonkwang University, Iksan, Republic of Korea.; Wonkwang-Oriental Medicines Research Institute, Wonkwang University, Iksan, Republic of Korea., Choi HY; Department of Oriental Pharmacy, College of Pharmacy, Wonkwang University, Iksan, Republic of Korea., Jung HJ; Department of Oriental Pharmacy, College of Pharmacy, Wonkwang University, Iksan, Republic of Korea.; Wonkwang-Oriental Medicines Research Institute, Wonkwang University, Iksan, Republic of Korea., Noh S; Graduate School of Techno Design, Kookmin University, Seoul, Republic of Korea., Cho M; Graduate School of Techno Design, Kookmin University, Seoul, Republic of Korea., Kang SS; Korea Dispensary Inc., Cheongju, Republic of Korea., Lee YM; Department of Oriental Pharmacy, College of Pharmacy, Wonkwang University, Iksan, Republic of Korea.; Wonkwang-Oriental Medicines Research Institute, Wonkwang University, Iksan, Republic of Korea.; The One Health Design Inc., Iksan, Republic of Korea.
Source: Frontiers in pharmacology [Front Pharmacol] 2025 Jul 24; Vol. 16, pp. 1617180. Date of Electronic Publication: 2025 Jul 24 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media] Country of Publication: Switzerland NLM ID: 101548923 Publication Model: eCollection Cited Medium: Print ISSN: 1663-9812 (Print) Linking ISSN: 16639812 NLM ISO Abbreviation: Front Pharmacol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:1663-9812
DOI:10.3389/fphar.2025.1617180