Giant extrachromosomal element "Inocle" potentially expands the adaptive capacity of the human oral microbiome.
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| Title: | Giant extrachromosomal element "Inocle" potentially expands the adaptive capacity of the human oral microbiome. |
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| Authors: | Kiguchi Y; Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Japan. yuya.kiguchi@edu.k.u-tokyo.ac.jp.; Laboratory for Symbiotic Microbiome Sciences, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan. yuya.kiguchi@edu.k.u-tokyo.ac.jp., Hamamoto N; Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Japan.; Medical & Biological Laboratories Co., Ltd., Tokyo, Japan., Kashima Y; Life Science Data Research Center, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Japan., Runtuwene LR; AIDS Research Center, National Institute of Infectious Diseases, Japan Institute for Health Security, Tokyo, Japan., Ishizaka A; Division of Infectious Diseases, Advanced Clinical Research Center, the Institute of Medical Science, The University of Tokyo, Tokyo, Japan., Kuze Y; Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Japan., Enokida T; Department of Head and Neck Medical Oncology, National Cancer Center Hospital East, Kashiwa, Japan., Tanaka N; Department of Head and Neck Medical Oncology, National Cancer Center Hospital East, Kashiwa, Japan., Tahara M; Department of Head and Neck Medical Oncology, National Cancer Center Hospital East, Kashiwa, Japan., Kageyama SI; Division of Cancer Immunology, Research Institute/ Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, Kashiwa, Japan.; Department of Radiation Oncology, National Cancer Center Hospital East, Kashiwa, Japan.; Division of Radiation Oncology and Particle Therapy, National Cancer Center Hospital East, Kashiwa, Japan., Fujisawa T; Department of Head and Neck Medical Oncology, National Cancer Center Hospital East, Kashiwa, Japan.; Translational Research Support Section, National Cancer Center Hospital East, Kashiwa, Japan.; Translational Research Sample Support Office, National Cancer Center Hospital East, Kashiwa, Japan., Yamashita R; Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Japan.; Division of Translational Informatics, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, Kashiwa, Japan., Kanai A; Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Japan., Tuda JSB; Faculty of Medicine, Sam Ratulangi University, Kampus Unsrat, Bahu Manado, Indonesia., Mizutani T; Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Japan.; AIDS Research Center, National Institute of Infectious Diseases, Japan Institute for Health Security, Tokyo, Japan.; Department of Diagnostic Testing and Technology Research, National Institute of Infectious Diseases, Japan Institute for Health Security, Tokyo, Japan., Suzuki Y; Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Japan. ysuzuki@edu.k.u-tokyo.ac.jp. |
| Source: | Nature communications [Nat Commun] 2025 Aug 11; Vol. 16 (1), pp. 7397. Date of Electronic Publication: 2025 Aug 11. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-025-62406-5 |
