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Hyperoside mitigates amphotericin B-induced nephrotoxicity in HK-2 cells via bioenergetic and oxidative stress modulation.

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Title: Hyperoside mitigates amphotericin B-induced nephrotoxicity in HK-2 cells via bioenergetic and oxidative stress modulation.
Authors: Elmorsy EM; Center for Health Research, Northern Border University, Arar, 73213, Saudi Arabia., Al Doghaither HA; Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, 21589, Saudi Arabia., Al-Ghafari AB; Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, 21589, Saudi Arabia.; Experimental Biochemistry Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, 21589, Saudi Arabia., Hifni BA; Department of Biology, Preparatory Year Program, Batterjee Medical College, Jeddah, 21442, Saudi Arabia., Jawad NMM; Department of Clinical Nutrition, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, 21589, Saudi Arabia., Hakim NA; Department of Clinical Nutrition, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, 21589, Saudi Arabia., Fawzy MS; Center for Health Research, Northern Border University, Arar, 73213, Saudi Arabia. manal.darwish@nbu.edu.sa., Aly NM; Department of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Suez Canal University, Ismailia, 41522, Egypt. nagwaaly@med.suez.edu.eg.
Source: BMC pharmacology & toxicology [BMC Pharmacol Toxicol] 2025 Aug 12; Vol. 26 (1), pp. 149. Date of Electronic Publication: 2025 Aug 12.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101590449 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-6511 (Electronic) Linking ISSN: 20506511 NLM ISO Abbreviation: BMC Pharmacol Toxicol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2050-6511
DOI:10.1186/s40360-025-00985-1