A fluorescence lifetime-based FLIM-timer for measuring the protein turnover of transcription factor Nrf2 in live cells.
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| Title: | A fluorescence lifetime-based FLIM-timer for measuring the protein turnover of transcription factor Nrf2 in live cells. |
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| Authors: | Dikovskaya D; Division of Cellular Medicine, University of Dundee School of Medicine, Dundee, DD1 9SY, UK. dina.dikovskaya@plymouth.ac.uk.; MRC Protein Phosphorylation and Ubiquitylation Unit, University of Dundee, Dundee, DD1 5EH, UK. dina.dikovskaya@plymouth.ac.uk.; Peninsula Medical School, Faculty of Health, University of Plymouth, Plymouth, PL4 8AA, UK. dina.dikovskaya@plymouth.ac.uk., Bento-Pereira C; Division of Cellular Medicine, University of Dundee School of Medicine, Dundee, DD1 9SY, UK., Shiga K; Division of Cellular Medicine, University of Dundee School of Medicine, Dundee, DD1 9SY, UK.; The Department of Advanced Health Science, Graduate School of Advanced Health Sciences, Saga University, Saga, Japan., Corno A; Division of Cellular Medicine, University of Dundee School of Medicine, Dundee, DD1 9SY, UK., Higgins M; Division of Cellular Medicine, University of Dundee School of Medicine, Dundee, DD1 9SY, UK., Toth R; MRC Reagents and Services, University of Dundee, Dundee, DD1 5EH, UK., Saurin AT; Division of Cellular Medicine, University of Dundee School of Medicine, Dundee, DD1 9SY, UK., Dinkova-Kostova AT; Division of Cellular Medicine, University of Dundee School of Medicine, Dundee, DD1 9SY, UK.; Department of Physiology, Pharmacology and Therapeutics, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA. |
| Source: | Scientific reports [Sci Rep] 2025 Aug 14; Vol. 15 (1), pp. 29772. Date of Electronic Publication: 2025 Aug 14. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2045-2322 |
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| DOI: | 10.1038/s41598-025-14721-6 |
