Comparative efficacy of first- versus second-line CDK4/6 inhibition in hormone receptor-positive, HER2-negative metastatic breast cancer.

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Title: Comparative efficacy of first- versus second-line CDK4/6 inhibition in hormone receptor-positive, HER2-negative metastatic breast cancer.
Authors: Ravani LV; Faculdade de Medicina da Universidade de São Paulo (FMUSP), São Paulo, Brazil., Bagheri Z; Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA., Brufsky AM; Division of Hematology/Oncology, Comprehensive Breast Cancer Center, University of Pittsburgh Medical Center, Magee Women's Center, Pittsburgh, PA, USA., Michelon I; Division of Hematology and Oncology, University of Virginia Comprehensive Cancer Center, Pelotas, USA., O'Regan R; University of Rochester Medical Center, Rochester, NY, USA., Lustberg M; Medical Oncology, Yale Cancer Center, Yale University, New Haven, CT, USA., Han H; Department of Breast Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA., Wang M; Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, OH, USA., Wander SA; Division of Hematology/Oncology, Department of Medicine, Massachusetts General Hospital Cancer Center, Harvard Medical School Massachusetts General Hospital, 55 Fruit St. Yawkey 9A, Boston, 02214, USA. swander@mgh.harvard.edu.
Source: Breast cancer research : BCR [Breast Cancer Res] 2025 Aug 13; Vol. 27 (1), pp. 146. Date of Electronic Publication: 2025 Aug 13.
Publication Type: Journal Article; Meta-Analysis; Systematic Review; Comparative Study
Journal Info: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 100927353 Publication Model: Electronic Cited Medium: Internet ISSN: 1465-542X (Electronic) Linking ISSN: 14655411 NLM ISO Abbreviation: Breast Cancer Res Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1465-542X
DOI:10.1186/s13058-025-02095-6