GRSF1 loss in THP-1 macrophages promotes senescence-associated transcription in neighboring fibroblasts.
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| Title: | GRSF1 loss in THP-1 macrophages promotes senescence-associated transcription in neighboring fibroblasts. |
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| Authors: | Lee Y; Molecular Aging Biology Laboratory (MABL), Dept of Biochemistry, College of Natural Science, Chungnam National University (CNU), Daejeon, 34134, Republic of Korea., Jo S; School of Biological Science and Technology, Chonnam National University, Gwangju, 61186, Republic of Korea., Lim MH; Molecular Aging Biology Laboratory (MABL), Dept of Biochemistry, College of Natural Science, Chungnam National University (CNU), Daejeon, 34134, Republic of Korea., Hwang S; Molecular Aging Biology Laboratory (MABL), Dept of Biochemistry, College of Natural Science, Chungnam National University (CNU), Daejeon, 34134, Republic of Korea., Jang S; Molecular Aging Biology Laboratory (MABL), Dept of Biochemistry, College of Natural Science, Chungnam National University (CNU), Daejeon, 34134, Republic of Korea., Kim K; Department of Emergency Medicine, CHA University School of Medicine, Seongnam, 13497, Republic of Korea., Yoon SJ; Environmental Disease Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Republic of Korea., Sima J; Laboratory of Aging Neuroscience and Neuropharmacology, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, 210009, China., Idda ML; Institute for Genetic and Biomedical Research (IRGB-CNR), Department of Biomedical Science, University of Sassari, Sassari , Italy., Kim KM; Department of Biological Sciences, Chungnam National University, Daejeon, Republic of Korea., Gorospe M; Laboratory of Genetics and Genomics, National Institute on Aging Intramural Research Program, National Institutes of Health, Baltimore, MD, USA., Park C; School of Biological Science and Technology, Chonnam National University, Gwangju, 61186, Republic of Korea. chungoo@jnu.ac.kr., Noh JH; Molecular Aging Biology Laboratory (MABL), Dept of Biochemistry, College of Natural Science, Chungnam National University (CNU), Daejeon, 34134, Republic of Korea. journi@cnu.ac.kr.; Dept of Biochemistry, College of Natural Science, CNU 99 Daehak-ro, Yuseong-gu, Daejeon, 34134, South Korea. journi@cnu.ac.kr. |
| Source: | Scientific reports [Sci Rep] 2025 Aug 14; Vol. 15 (1), pp. 29851. Date of Electronic Publication: 2025 Aug 14. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2045-2322 |
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| DOI: | 10.1038/s41598-025-11385-0 |
