A patient-derived decellularized extracellular matrix hydrogel as a biomimetic scaffold for advanced 3D colorectal cancer modeling.

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Title: A patient-derived decellularized extracellular matrix hydrogel as a biomimetic scaffold for advanced 3D colorectal cancer modeling.
Authors: D'Angelo E; General Surgery 3, Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy; NanoInspired biomedicine lab, Fondazione Istituto di Ricerca Pediatrica Città della Speranza, Padova, Italy; Biobanca di Ricerca, Azienda Ospedale-Università di Padova, Padova, Italy. Electronic address: edoardo.dangelo@unipd.it., Marangio A; General Surgery 3, Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy., Sensi F; NanoInspired biomedicine lab, Fondazione Istituto di Ricerca Pediatrica Città della Speranza, Padova, Italy; Department of Gynecology and Obstetrics, Division of Women and Children's Health, University of Padova, Padova, Italy., Zanrè E; Department of Industrial Engineering (DII), University of Padova, Padova, Italy; Fondazione Istituto di Ricerca Pediatrica Cittá Della Speranza (IRP)-Lab BIAMET, Padova, Italy; Department of Biomedical Sciences, University of Padova, Padova, Italy., Steffan A; Immunopathology and Cancer Biomarkers, CRO Aviano, National Cancer Institute, IRCCS, Aviano, Italy., Repetto O; Immunopathology and Cancer Biomarkers, CRO Aviano, National Cancer Institute, IRCCS, Aviano, Italy., Rampado R; Laboratory of Precision Nanomedicine, Shmunis School of Biomedicine and Cancer Research, TelAviv University, Tel Aviv-Yafo 69978, Israel., Giomo M; Department of Industrial Engineering (DII), University of Padova, Padova, Italy., Fassan M; Department of Medicine, Unit of Surgical Pathology, University of Padua, Padua, Italy; Veneto Institute of Oncology, IOV-IRCCS, Padua, Italy., Spolverato G; General Surgery 3, Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy; Biobanca di Ricerca, Azienda Ospedale-Università di Padova, Padova, Italy., Cimetta E; Department of Industrial Engineering (DII), University of Padova, Padova, Italy; Fondazione Istituto di Ricerca Pediatrica Cittá Della Speranza (IRP)-Lab BIAMET, Padova, Italy., Agostini M; General Surgery 3, Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy; NanoInspired biomedicine lab, Fondazione Istituto di Ricerca Pediatrica Città della Speranza, Padova, Italy; Biobanca di Ricerca, Azienda Ospedale-Università di Padova, Padova, Italy. Electronic address: m.agostini@unipd.it.
Source: Biomaterials advances [Biomater Adv] 2026 Jan; Vol. 178, pp. 214438. Date of Electronic Publication: 2025 Aug 05.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 9918383886206676 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2772-9508 (Electronic) Linking ISSN: 27729508 NLM ISO Abbreviation: Biomater Adv Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2772-9508
DOI:10.1016/j.bioadv.2025.214438