Circulating genomic landscape following cyclin-dependent kinase 4/6 inhibitors exposure in HR + /HER2- metastatic breast cancer: a retrospective multi-institutional Consortium analysis.

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Title: Circulating genomic landscape following cyclin-dependent kinase 4/6 inhibitors exposure in HR + /HER2- metastatic breast cancer: a retrospective multi-institutional Consortium analysis.
Authors: Pontolillo L; Division of Hematology-Oncology, Weill Cornell Medicine, New York, NY, USA. lep4008@med.cornell.edu.; Department of Translational Medicine and Surgery, Università Cattolica del Sacro Cuore, Rome, Italy. lep4008@med.cornell.edu., Davis AA; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA., Gerratana L; Department of Medical Oncology, CRO Aviano National Cancer Institute, IRCCS, Aviano, Italy.; Department of Medicine, University of Udine, Via Chiusaforte, Udine, Italy., Medford AJ; Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA., Wang J; Division of Hematology-Oncology, Weill Cornell Medicine, New York, NY, USA., Nicolo' E; Division of Hematology-Oncology, Weill Cornell Medicine, New York, NY, USA., Clifton K; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA., Velimirovic M; Taussig Cancer Institute, Cleveland Clinic Foundation, Cleveland, OH, USA., Warrior S; Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL, USA., Podany E; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA., Andreopoulou E; Division of Hematology-Oncology, Weill Cornell Medicine, New York, NY, USA., Serafini MS; Division of Hematology-Oncology, Weill Cornell Medicine, New York, NY, USA., Munoz-Arcos L; Division of Hematology-Oncology, Weill Cornell Medicine, New York, NY, USA., Molteni E; Division of Hematology-Oncology, Weill Cornell Medicine, New York, NY, USA.; Department of Medicine, University of Udine, Via Chiusaforte, Udine, Italy., Lipsyc-Sharf M; David Geffen School of Medicine at UCLA, Los Angeles, USA., Gianni C; Medical Oncology, Breast & GYN Unit, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) 'Dino Amadori', Meldola, Italy., Bayou N; Division of Hematology-Oncology, Weill Cornell Medicine, New York, NY, USA.; Human Genetics Laboratory (LR99ES10), Faculty of Medicine of Tunis, University of Tunis El Manar, Tunis, Tunisia., Dai CS; Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA., Giannarelli D; Facility of Epidemiology and Biostatistics, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy., Bria E; Department of Translational Medicine and Surgery, Università Cattolica del Sacro Cuore, Rome, Italy.; Medical Oncology, Ospedale Isola Tiberina-Gemelli Isola, Rome, Italy., Ma CX; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA., Bardia A; Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, USA.; David Geffen School of Medicine at UCLA, Los Angeles, USA., Reduzzi C; Division of Hematology-Oncology, Weill Cornell Medicine, New York, NY, USA., Cristofanilli M; Division of Hematology-Oncology, Weill Cornell Medicine, New York, NY, USA.
Source: NPJ breast cancer [NPJ Breast Cancer] 2025 Aug 16; Vol. 11 (1), pp. 93. Date of Electronic Publication: 2025 Aug 16.
Publication Type: Journal Article
Journal Info: Publisher: Breast Cancer Research Foundation Country of Publication: United States NLM ID: 101674891 Publication Model: Electronic Cited Medium: Print ISSN: 2374-4677 (Print) Linking ISSN: 23744677 NLM ISO Abbreviation: NPJ Breast Cancer Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:2374-4677
DOI:10.1038/s41523-025-00802-2