Inhibition of inducible nitric oxide synthase (iNOS) alleviates thoracic aortic aneurysm by regulating mitochondrial dynamics.

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Title: Inhibition of inducible nitric oxide synthase (iNOS) alleviates thoracic aortic aneurysm by regulating mitochondrial dynamics.
Authors: Zheng ZF; Department of Cardiovascular Surgery, Shanxi Bethune Hospital, Taiyuan, China., Zhang JJ; Key Laboratory of Cellular Physiology at Shanxi Medical University, Ministry of Education, Taiyuan, China; Department of Physiology, Shanxi Medical University, Taiyuan, China., Wu LF; Key Laboratory of Cellular Physiology at Shanxi Medical University, Ministry of Education, Taiyuan, China; Department of Pathophysiology, Shanxi Medical University, Taiyuan, China., Wang XN; Department of Cardiovascular Surgery, Shanxi Bethune Hospital, Taiyuan, China., Zhang X; Key Laboratory of Cellular Physiology at Shanxi Medical University, Ministry of Education, Taiyuan, China; Department of Physiology, Shanxi Medical University, Taiyuan, China., Zou BB; Institute for Pathogenesis and Clinical Translational Research of Esophageal Cancer, Shanxi Medical University, China., Zhao XY; Department of Cardiovascular Surgery, Shanxi Bethune Hospital, Taiyuan, China., Zheng JY; Department of Cardiovascular Surgery, Shanxi Bethune Hospital, Taiyuan, China., Wang KF; Department of Cardiology, The First Hospital of Shanxi Medical University, Taiyuan, China., Guo J; Department of Cardiology, The First Hospital of Shanxi Medical University, Taiyuan, China., Du WJ; Department of Cell Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Beijing, China. Electronic address: wenjingdu@ibms.pumc.edu.cn., Cao JM; Key Laboratory of Cellular Physiology at Shanxi Medical University, Ministry of Education, Taiyuan, China; Department of Physiology, Shanxi Medical University, Taiyuan, China. Electronic address: caojimin@sxmu.edu.cn.
Source: European journal of pharmacology [Eur J Pharmacol] 2025 Oct 15; Vol. 1005, pp. 178071. Date of Electronic Publication: 2025 Aug 15.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0712 (Electronic) Linking ISSN: 00142999 NLM ISO Abbreviation: Eur J Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1879-0712
DOI:10.1016/j.ejphar.2025.178071