Fc-modification of anti-PcrV gene-encoded antibodies modulates complement-mediated killing of Pseudomonas aeruginosa.
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| Title: | Fc-modification of anti-PcrV gene-encoded antibodies modulates complement-mediated killing of Pseudomonas aeruginosa. |
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| Authors: | Eisenhauer J; Perelman School of Medicine University of Pennsylvania, Philadelphia, PA, United States.; Vaccine & Immunotherapy Center, The Wistar Institute of Anatomy and Biology, Philadelphia, PA, United States., Dublin S; Department of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, WV, United States., Choi J; Vaccine & Immunotherapy Center, The Wistar Institute of Anatomy and Biology, Philadelphia, PA, United States., Trachtman AR; Vaccine & Immunotherapy Center, The Wistar Institute of Anatomy and Biology, Philadelphia, PA, United States., Chu JD; Vaccine & Immunotherapy Center, The Wistar Institute of Anatomy and Biology, Philadelphia, PA, United States., Custodio-Zegarra D; Vaccine & Immunotherapy Center, The Wistar Institute of Anatomy and Biology, Philadelphia, PA, United States., Bharti S; Vaccine & Immunotherapy Center, The Wistar Institute of Anatomy and Biology, Philadelphia, PA, United States., Bhardwaj B; Vaccine & Immunotherapy Center, The Wistar Institute of Anatomy and Biology, Philadelphia, PA, United States., Bai S; Paul G. Allen School for Global Health, College of Veterinary Medicine, Washington State University, Pullman, WA, United States., Witt WT; Department of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, WV, United States., Gutierrez MP; Department of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, WV, United States., Miller SJ; Department of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, WV, United States., Flowers K; Vaccine & Immunotherapy Center, The Wistar Institute of Anatomy and Biology, Philadelphia, PA, United States., Smith TRF; Inovio Pharmaceuticals, Plymouth Meeting, PA, United States., Gunn BM; Paul G. Allen School for Global Health, College of Veterinary Medicine, Washington State University, Pullman, WA, United States., Barbier M; Department of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, WV, United States., Parzych EM; Vaccine & Immunotherapy Center, The Wistar Institute of Anatomy and Biology, Philadelphia, PA, United States., Weiner DB; Vaccine & Immunotherapy Center, The Wistar Institute of Anatomy and Biology, Philadelphia, PA, United States., Patel A; Vaccine & Immunotherapy Center, The Wistar Institute of Anatomy and Biology, Philadelphia, PA, United States. |
| Source: | Frontiers in immunology [Front Immunol] 2025 Jul 31; Vol. 16, pp. 1618297. Date of Electronic Publication: 2025 Jul 31 (Print Publication: 2025). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1664-3224 |
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| DOI: | 10.3389/fimmu.2025.1618297 |
