Serotonin and psilocybin activate 5-HT1B receptors to suppress cortical signaling through the claustrum.
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| Title: | Serotonin and psilocybin activate 5-HT |
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| Authors: | Madden MB; Department of Pharmacology and Physiology, School of Medicine, University of Maryland, Baltimore, MD, USA., Schaefgen C; Department of Pharmacology and Physiology, School of Medicine, University of Maryland, Baltimore, MD, USA., Vedak B; Department of Pharmacology and Physiology, School of Medicine, University of Maryland, Baltimore, MD, USA.; Department of Psychiatry, School of Medicine, University of Maryland, Baltimore, MD, USA., Kwon J; Department of Pharmacology and Physiology, School of Medicine, University of Maryland, Baltimore, MD, USA., Pedra KSD; Department of Pharmacology and Physiology, School of Medicine, University of Maryland, Baltimore, MD, USA., Sheats SH; Department of Pharmacology and Physiology, School of Medicine, University of Maryland, Baltimore, MD, USA., Puche AC; Department of Neurobiology, School of Medicine, University of Maryland, Baltimore, MD, USA.; University of Maryland Medicine Institute for Neuroscience Discovery, University of Maryland, Baltimore, MD, USA., Wolff SBE; Department of Pharmacology and Physiology, School of Medicine, University of Maryland, Baltimore, MD, USA.; University of Maryland Medicine Institute for Neuroscience Discovery, University of Maryland, Baltimore, MD, USA., Mathur BN; Department of Pharmacology and Physiology, School of Medicine, University of Maryland, Baltimore, MD, USA. bmathur@som.umaryland.edu.; Department of Psychiatry, School of Medicine, University of Maryland, Baltimore, MD, USA. bmathur@som.umaryland.edu.; University of Maryland Medicine Institute for Neuroscience Discovery, University of Maryland, Baltimore, MD, USA. bmathur@som.umaryland.edu.; Kahlert Institute for Addiction Medicine, University of Maryland, Baltimore, MD, USA. bmathur@som.umaryland.edu. |
| Source: | Nature communications [Nat Commun] 2025 Aug 19; Vol. 16 (1), pp. 7733. Date of Electronic Publication: 2025 Aug 19. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-025-62980-8 |
