Single-versus double-layer uterine closure at the time of cesarean delivery and risk of uterine scar niche: a systematic review and meta-analysis of randomized trials.

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Title: Single-versus double-layer uterine closure at the time of cesarean delivery and risk of uterine scar niche: a systematic review and meta-analysis of randomized trials.
Authors: Dominoni M; Department of Clinical, Surgical, Diagnostic and Paediatric Sciences, University of Pavia, Corso Strada Nuova, 65, 27100, Pavia, Italy.; Department of Obstetrics and Gynecology, Fondazione IRCCS Policlinico San Matteo, Viale Camillo Golgi 19, 27100, Pavia, Italy., Torella M; Department of Woman, Child and General and Specialized Surgery, Obstetrics and Gynaecology Unit, University of Campania 'Luigi Vanvitelli', Naples, Italy., Molitierno R; Department of Woman, Child and General and Specialized Surgery, Obstetrics and Gynaecology Unit, University of Campania 'Luigi Vanvitelli', Naples, Italy., Fordellone M; Medical Statistics Unit, University of Campania Luigi Vanvitelli, Naples, Italy., Saccone G; Department of Neuroscience, Reproductive Sciences and Dentistry, School of Medicine, University of Naples Federico II, Naples, Italy., Colacurci D; Department of Public Health, School of Medicine, University of Naples Federico II, Naples, Italy., Laganà AS; Unit of Obstetrics and Gynecology, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (PROMISE), 'Paolo Giaccone' Hospital, University of Palermo, 90127, Palermo, Italy., Pano MR; Department of Clinical, Surgical, Diagnostic and Paediatric Sciences, University of Pavia, Corso Strada Nuova, 65, 27100, Pavia, Italy. martinarita.pano01@universitadipavia.it.; Department of Obstetrics and Gynecology, Fondazione IRCCS Policlinico San Matteo, Viale Camillo Golgi 19, 27100, Pavia, Italy. martinarita.pano01@universitadipavia.it., Gardella B; Department of Clinical, Surgical, Diagnostic and Paediatric Sciences, University of Pavia, Corso Strada Nuova, 65, 27100, Pavia, Italy.; Department of Obstetrics and Gynecology, Fondazione IRCCS Policlinico San Matteo, Viale Camillo Golgi 19, 27100, Pavia, Italy., La Verde M; Department of Woman, Child and General and Specialized Surgery, Obstetrics and Gynaecology Unit, University of Campania 'Luigi Vanvitelli', Naples, Italy.
Source: Archives of gynecology and obstetrics [Arch Gynecol Obstet] 2025 Oct; Vol. 312 (4), pp. 1095-1106. Date of Electronic Publication: 2025 Aug 20.
Publication Type: Journal Article; Systematic Review; Meta-Analysis
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 8710213 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0711 (Electronic) Linking ISSN: 09320067 NLM ISO Abbreviation: Arch Gynecol Obstet Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1432-0711
DOI:10.1007/s00404-025-08151-y