Unbiased mapping of cereblon neosubstrate landscape by high-throughput proteomics.
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| Title: | Unbiased mapping of cereblon neosubstrate landscape by high-throughput proteomics. |
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| Authors: | Steger M; NEOsphere Biotechnologies GmbH, Martinsried, Germany., Nishiguchi G; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, USA., Wu Q; Department of Surgery, St. Jude Children's Research Hospital, Memphis, TN, USA., Schwalb B; NEOsphere Biotechnologies GmbH, Martinsried, Germany., Shashikadze B; NEOsphere Biotechnologies GmbH, Martinsried, Germany., McGowan K; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, USA., Actis M; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, USA., Aggarwal A; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, USA., Shi Z; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, USA., Price J; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, USA., Mayasundari A; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, USA., Yang L; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, USA., Bednarz AH; NEOsphere Biotechnologies GmbH, Martinsried, Germany., Machata S; NEOsphere Biotechnologies GmbH, Martinsried, Germany., Graef T; NEOsphere Biotechnologies GmbH, Martinsried, Germany., Bartoschek D; NEOsphere Biotechnologies GmbH, Martinsried, Germany., Demichev V; Department of Biochemistry, Charité - Universitätsmedizin Berlin, Berlin, Germany., Ohmayer U; NEOsphere Biotechnologies GmbH, Martinsried, Germany., Yang J; Department of Surgery, St. Jude Children's Research Hospital, Memphis, TN, USA. jun.yang2@stjude.org.; Department of Pathology and Laboratory Medicine, College of Medicine, The University of Tennessee Health Science Center, Memphis, TN, USA. jun.yang2@stjude.org.; College of Graduate Health Sciences, University of Tennessee Health Science Center, Memphis, TN, USA. jun.yang2@stjude.org., Daub H; NEOsphere Biotechnologies GmbH, Martinsried, Germany. henrik.daub@neospherebiotech.com., Rankovic Z; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, USA. zoran.rankovic@icr.ac.uk.; Centre for Protein Degradation, The Institute of Cancer Research, London, UK. zoran.rankovic@icr.ac.uk. |
| Source: | Nature communications [Nat Commun] 2025 Aug 20; Vol. 16 (1), pp. 7773. Date of Electronic Publication: 2025 Aug 20. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-025-62829-0 |
