Evidence for reduced synaptic protein SNAP-25 in cerebrospinal fluid in major depressive disorder and schizophrenia.

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Title: Evidence for reduced synaptic protein SNAP-25 in cerebrospinal fluid in major depressive disorder and schizophrenia.
Authors: Steinacker P; Department of Neurology, Martin Luther University Halle Wittenberg, Halle (Saale), Germany., Werner L; Department of Neurology, Ulm University Hospital, Ulm, Germany., Tarabuko A; Department of Neurology, Martin Luther University Halle Wittenberg, Halle (Saale), Germany., Al-Ali I; Department of Neurology, Martin Luther University Halle Wittenberg, Halle (Saale), Germany., Mechawar N; Department of Psychiatry, McGill University, Montreal, Quebec, Canada., Pryce CR; University Hospital of Psychiatry, University of Zurich, Zurich, Switzerland., Cattane N; Biological Psychiatry Unit, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy., Poggi G; University Hospital of Psychiatry, University of Zurich, Zurich, Switzerland., Al Shweiki MR; Department of Neurology, Ulm University Hospital, Ulm, Germany., Graf H; Department of Psychiatry and Psychotherapy III, Ulm University Hospital, Ulm, Germany., Großkopf H; Department of Neurology, Martin Luther University Halle Wittenberg, Halle (Saale), Germany., Halbgebauer S; Department of Neurology, Ulm University Hospital, Ulm, Germany., Oeckl P; Department of Neurology, Ulm University Hospital, Ulm, Germany.; DZNE Standort Ulm, Ulm, Germany., Barba L; Department of Neurology, Martin Luther University Halle Wittenberg, Halle (Saale), Germany., Meier L; Department of Neurology, Ulm University Hospital, Ulm, Germany., Abu-Rumeileh S; Department of Neurology, Martin Luther University Halle Wittenberg, Halle (Saale), Germany., Marston H; CNS Diseases Research, Boehringer Ingelheim Pharma GmbH and Co. KG, Biberach an der Riss, Germany., Bornemann KD; CNS Diseases Research, Boehringer Ingelheim Pharma GmbH and Co. KG, Biberach an der Riss, Germany., Hengerer B; CNS Diseases Research, Boehringer Ingelheim Pharma GmbH and Co. KG, Biberach an der Riss, Germany., Danzer KM; Department of Neurology, Ulm University Hospital, Ulm, Germany.; DZNE Standort Ulm, Ulm, Germany., Schönfeldt-Lecuona C; Department of Psychiatry and Psychotherapy III, Ulm University Hospital, Ulm, Germany., Otto M; Department of Neurology, Martin Luther University Halle Wittenberg, Halle (Saale), Germany markus.otto@uk-halle.de.; Department of Neurology, Ulm University Hospital, Ulm, Germany.
Source: BMJ mental health [BMJ Ment Health] 2025 Aug 21; Vol. 28 (1). Date of Electronic Publication: 2025 Aug 21.
Publication Type: Journal Article
Journal Info: Publisher: BMJ Country of Publication: England NLM ID: 9918521385306676 Publication Model: Electronic Cited Medium: Internet ISSN: 2755-9734 (Electronic) Linking ISSN: 27559734 NLM ISO Abbreviation: BMJ Ment Health Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2755-9734
DOI:10.1136/bmjment-2025-301752