Changes in Gray Matter Morphology and White Matter Microstructure Across the Adult Lifespan in People With Temporal Lobe Epilepsy.

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Title: Changes in Gray Matter Morphology and White Matter Microstructure Across the Adult Lifespan in People With Temporal Lobe Epilepsy.
Authors: Chen J; Multimodal Imaging and Connectome Analysis Laboratory, McConnell Brain Imaging Centre, Montreal Neurological Institute and Hospital, McGill University, Montreal, Quebec, Canada., Ngo A; Multimodal Imaging and Connectome Analysis Laboratory, McConnell Brain Imaging Centre, Montreal Neurological Institute and Hospital, McGill University, Montreal, Quebec, Canada., Rodriguez-Cruces R; Multimodal Imaging and Connectome Analysis Laboratory, McConnell Brain Imaging Centre, Montreal Neurological Institute and Hospital, McGill University, Montreal, Quebec, Canada., Royer J; Multimodal Imaging and Connectome Analysis Laboratory, McConnell Brain Imaging Centre, Montreal Neurological Institute and Hospital, McGill University, Montreal, Quebec, Canada., Caligiuri ME; Neuroscience Research Center, University Magna Græcia, Catanzaro, Italy., Gambardella A; Neuroscience Research Center, University Magna Græcia, Catanzaro, Italy.; Institute of Neurology, University Magna Græcia, Catanzaro, Italy., Concha L; Institute of Neurobiology, Universidad Nacional Autónoma de México, Querétaro., Keller SS; Institute of Systems, Molecular and Integrative Biology, University of Liverpool, United Kingdom.; Walton Centre NHS Foundation Trust, Liverpool, United Kingdom., Cendes F; Department of Neurology, University of Campinas-UNICAMP, Campinas, São Paulo, Brazil., Yasuda CL; Department of Neurology, University of Campinas-UNICAMP, Campinas, São Paulo, Brazil., Alvim MKM; Department of Neurology, University of Campinas-UNICAMP, Campinas, São Paulo, Brazil., Bonilha L; Department of Neurology, Emory University, Atlanta, GA., Gleichgerrcht E; Department of Neurology, Emory University, Atlanta, GA., Focke NK; Department of Neurology, University of Medicine Göttingen, Germany., Kreilkamp BAK; Department of Neurology, University of Medicine Göttingen, Germany., Domin M; Institute of Diagnostic Radiology and Neuroradiology, Functional Imaging Unit, University Medicine Greifswald, Germany., Von Podewils F; Department of Neurology, University Medicine Greifswald, Epilepsy Center, Germany., Langner S; Institute of Diagnostic Radiology and Neuroradiology, University Medicine Greifswald, Germany., Rummel C; Support Center for Advanced Neuroimaging (SCAN), University Institute of Diagnostic and Interventional Neuroradiology, University Hospital Bern, Switzerland., Wiest R; Support Center for Advanced Neuroimaging (SCAN), University Institute of Diagnostic and Interventional Neuroradiology, University Hospital Bern, Switzerland., Martin P; Department of Neurology and Epileptology, Hertie Institute for Clinical Brain Research, University of Tübingen, Germany., Kotikalapudi R; Department of Neurology, University of Medicine Göttingen, Germany.; Department of Neurology and Epileptology, Hertie Institute for Clinical Brain Research, University of Tübingen, Germany., Bender B; Diagnostic and Interventional Neuroradiology, University Hospital Tübingen, Germany., O'Brien TJ; Department of Neuroscience, Central Clinical School, Alfred Hospital, Monash University, Melbourne, Australia.; Departments of Medicine and Radiology, The Royal Melbourne Hospital, The University of Melbourne, Parkville, Australia., Sinclair B; Department of Neuroscience, Central Clinical School, Alfred Hospital, Monash University, Melbourne, Australia.; Departments of Medicine and Radiology, The Royal Melbourne Hospital, The University of Melbourne, Parkville, Australia., Vivash L; Department of Neuroscience, Central Clinical School, Alfred Hospital, Monash University, Melbourne, Australia.; Departments of Medicine and Radiology, The Royal Melbourne Hospital, The University of Melbourne, Parkville, Australia., Kwan P; Departments of Medicine and Radiology, The Royal Melbourne Hospital, The University of Melbourne, Parkville, Australia., Desmond P; Departments of Medicine and Radiology, The Royal Melbourne Hospital, The University of Melbourne, Parkville, Australia., Lui E; Departments of Medicine and Radiology, The Royal Melbourne Hospital, The University of Melbourne, Parkville, Australia., Duma GM; Scientific Institute IRCCS E. Medea, Epilepsy Unit, Conegliano, Italy., Bonanni P; Scientific Institute IRCCS E. Medea, Epilepsy Unit, Conegliano, Italy., Ballerini A; Department of Biomedical, Metabolic and Neural Science, University of Modena and Reggio Emilia, Italy., Vaudano AE; Department of Biomedical, Metabolic and Neural Science, University of Modena and Reggio Emilia, Italy.; Neurology Unit, OCB Hospital, Azienda Ospedaliera-Universitaria, Modena, Italy., Meletti S; Department of Biomedical, Metabolic and Neural Science, University of Modena and Reggio Emilia, Italy.; Neurology Unit, OCB Hospital, Azienda Ospedaliera-Universitaria, Modena, Italy., Tondelli M; Department of Biomedical, Metabolic and Neural Science, University of Modena and Reggio Emilia, Italy.; Primary Care Department, Azienda Sanitaria Locale di Modena, Italy., Alhusaini S; Department of Molecular and Cellular Therapeutics, The Royal College of Surgeons in Ireland, Dublin.; Department of Neurology, Alpert Medical School of Brown University, Providence, RI., Doherty CP; Department of Neurology, St James' Hospital, Dublin, Ireland.; FutureNeuro SFI Research Centre, Dublin, Ireland., Cavalleri G; Department of Molecular and Cellular Therapeutics, The Royal College of Surgeons in Ireland, Dublin.; FutureNeuro SFI Research Centre, Dublin, Ireland., Delanty N; Department of Molecular and Cellular Therapeutics, The Royal College of Surgeons in Ireland, Dublin.; FutureNeuro SFI Research Centre, Dublin, Ireland., Kalviainen R; Epilepsy Center, Neuro Center, Kuopio University Hospital, Member of the European Reference Network for Rare and Complex Epilepsies EpiCARE, Finland.; Faculty of Health Sciences, School of Medicine, Institute of Clinical Medicine, University of Eastern Finland, Kuopio., Jackson GD; Florey Institute of Neuroscience and Mental Health, University of Melbourne, Australia., Kowalczyk M; Florey Institute of Neuroscience and Mental Health, University of Melbourne, Australia., Mascalchi M; Neuroradiology Research Program, Meyer Children Hospital of Florence, University of Florence, Italy., Semmelroch MKHG; Florey Institute of Neuroscience and Mental Health, University of Melbourne, Australia., Thomas RH; Transitional and Clinical Research Institute, Newcastle University, United Kingdom., Soltanian-Zadeh H; Contol and Intelligent Processing Center of Excellence (CIPCE), School of Electrical and Computer Engineering, University of Tehran, Iran.; Departments of Research Administration and Radiology, Henry Ford Health System, Detroit, MI., Davoodi-Bojd E; Department of Neurology, Henry Ford Health System, Detroit, MI., Zhang J; Cognitive Science Department, Xiamen University, China., Lenge M; Child Neurology Unit and Laboratories, Neuroscience Department, Meyer Children's Hospital IRCCS, Florence, Italy., Guerrini R; Child Neurology Unit and Laboratories, Neuroscience Department, Meyer Children's Hospital IRCCS, Florence, Italy.; Department of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, Italy., Bartolini E; IRCCS Stella Maris Foundation, Pisa, Italy., Hamandi K; Cardiff University Brain Research Imaging Centre (CUBRIC), College of Biomedical and Life Sciences, Cardiff University, United Kingdom.; The Welsh Epilepsy Unit, Department of Neurology, University Hospital of Wales, Cardiff, United Kingdom., Foley S; Cardiff University Brain Research Imaging Centre (CUBRIC), College of Biomedical and Life Sciences, Cardiff University, United Kingdom., Rüber T; Department of Neuroradiology, University Hospital Bonn, Germany.; Department of Epileptology, University Hospital Bonn, Germany., Bauer T; Department of Neuroradiology, University Hospital Bonn, Germany.; Department of Epileptology, University Hospital Bonn, Germany., Weber B; Institute of Experimental Epileptology and Cognition Research, University Hospital Bonn, Germany., Caldairou B; Neuroimaging of Epilepsy Laboratory, McConnell Brain Imaging Centre, Montreal Neurological Institute and Hospital, McGill University, Quebec, Canada., Depondt C; Department of Neurology, Hôpital Erasme, Hôpital Universitaire de Bruxelles (HUB), Université Libre de Bruxelles, Belgium., Absil J; Department of Radiology, Hôpital Erasme, Université Libre de Bruxelles, Belgium., Carr SJA; School of Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, United Kingdom., Abela E; School of Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, United Kingdom., Richardson MP; School of Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, United Kingdom., Devinsky O; Department of Neurology, NYU Grossman School of Medicine, New York, USA., Pardoe HR; Department of Neurology, NYU Grossman School of Medicine, New York, USA., Severino M; IRCCS Istituto Giannina Gaslini, Genova, Italy., Striano P; IRCCS Istituto Giannina Gaslini, Genova, Italy.; Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Italy., Tortora D; Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Italy., Kaestner E; Department of Radiation Medicine and Applied Sciences, Department of Psychiatry, Center for Multimodal Imaging and Genetics, University of California San Diego, La Jolla., Hatton SN; Department of Neurosciences, Center for Multimodal Imaging and Genetics, University of California San Diego, La Jolla., Arienzo D; Department of Radiation Medicine and Applied Sciences, Department of Psychiatry, Center for Multimodal Imaging and Genetics, University of California San Diego, La Jolla., Vos SB; Department of Clinical and Experimental Epilepsy, UCL Queen Square Institute of Neurology, London, United Kingdom.; Chalfont Centre for Epilepsy, Bucks, United Kingdom.; Centre for Medical Image Computing, University College London, United Kingdom., Ryten M; Department of Clinical and Experimental Epilepsy, UCL Queen Square Institute of Neurology, London, United Kingdom.; MRI Unit, Epilepsy Society, Chalfont St Peter, Bucks, United Kingdom., Taylor PN; Department of Clinical and Experimental Epilepsy, UCL Queen Square Institute of Neurology, London, United Kingdom.; CNNP Lab, ICOS Group, Newcastle University, United Kingdom., Duncan JS; Department of Clinical and Experimental Epilepsy, UCL Queen Square Institute of Neurology, London, United Kingdom.; Chalfont Centre for Epilepsy, Bucks, United Kingdom., Whelan CD; Department of Molecular and Cellular Therapeutics, The Royal College of Surgeons in Ireland, Dublin., Galovic M; Department of Neurology, Clinical Neuroscience Center, University Hospital and University of Zürich, Switzerland., Winston GP; Department of Clinical and Experimental Epilepsy, UCL Queen Square Institute of Neurology, London, United Kingdom.; Chalfont Centre for Epilepsy, Bucks, United Kingdom.; Division of Neurology, Department of Medicine, Queen's University, Kingston, Ontario, Canada., Thomopoulos SI; Imaging Genetics Center, Mark & Mary Stevens Institute for Neuroimaging and Informatics, Keck School of Medicine, University of Southern California, Los Angeles., Thompson PM; Imaging Genetics Center, Mark & Mary Stevens Institute for Neuroimaging and Informatics, Keck School of Medicine, University of Southern California, Los Angeles., Sisodiya SM; Department of Clinical and Experimental Epilepsy, UCL Queen Square Institute of Neurology, London, United Kingdom.; Chalfont Centre for Epilepsy, Bucks, United Kingdom., Labate A; Neurophysiopathology and Movement Disorders Clinic, Regional Epilepsy Center, University of Messina, Italy., Mcdonald C; Department of Radiation Medicine and Applied Sciences, Department of Psychiatry, Center for Multimodal Imaging and Genetics, University of California San Diego, La Jolla., Caciagli L; Department of Clinical and Experimental Epilepsy, UCL Queen Square Institute of Neurology, London, United Kingdom.; MRI Unit, Epilepsy Society, Chalfont St Peter, Bucks, United Kingdom., Bernasconi N; Neuroimaging of Epilepsy Laboratory, McConnell Brain Imaging Centre, Montreal Neurological Institute and Hospital, McGill University, Quebec, Canada., Bernasconi A; Neuroimaging of Epilepsy Laboratory, McConnell Brain Imaging Centre, Montreal Neurological Institute and Hospital, McGill University, Quebec, Canada., Lariviere S; Center for Brain Circuit Therapeutics, Brigham and Women's Hospital, Harvard University, Boston, MA.; Center for Sherbrooke Laboratory for Integrative Connectomics, Centre de Recherche du CHUS, Université de Sherbrooke, Quebec, Canada; and., Schrader DV; BC Children's Hospital, University of British Columbia, Vancouver, Canada., Bernhardt BC; Multimodal Imaging and Connectome Analysis Laboratory, McConnell Brain Imaging Centre, Montreal Neurological Institute and Hospital, McGill University, Montreal, Quebec, Canada.
Source: Neurology [Neurology] 2025 Sep 23; Vol. 105 (6), pp. e213688. Date of Electronic Publication: 2025 Aug 22.
Publication Type: Journal Article
Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0401060 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1526-632X (Electronic) Linking ISSN: 00283878 NLM ISO Abbreviation: Neurology Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1526-632X
DOI:10.1212/WNL.0000000000213688