Red light photodynamic therapy with 10% aminolevulinic acid gel showed efficacy for treatment of superficial basal cell carcinoma in a randomized, vehicle controlled, double-blind, multicenter phase III study.

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Title: Red light photodynamic therapy with 10% aminolevulinic acid gel showed efficacy for treatment of superficial basal cell carcinoma in a randomized, vehicle controlled, double-blind, multicenter phase III study.
Authors: Schlesinger T; Clinical Research Center of the Carolinas, Charleston, South Carolina., Chapman MS; Dept. Of Dermatology, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire., Tu JH; Skin Search of Rochester, Rochester, New York., Cohen JL; AboutSkin Dermatology & Derm Surgery, Greenwood Village, Colorado., Strasswimmer J; Dermatology Associates PA of the Palm Beaches, Delray Location, Delray Beach, Florida., Zeitouni NC; Medical Dermatology Specialists, Phoenix, Arizona., Torres A; UF Department of Dermatology, University of Florida, Gainesville, Florida., Jazayeri SS; Alliance Dermatology & Mohs Center, Phoenix, Arizona., Goldman MP; Cosmetic Laser and Dermatology: A Platinum Dermatology Company, San Diego, California., Ibrahim SF; Rochester Dermatologic Surgery, Victor, New York., Lain EL; Austin Institute for Clinical Research, Inc, Pflugerville, Texas., Couvillion MP; Austin Institute for Clinical Research, Inc, Houston, Texas., Bruce S; Austin Institute for Clinical Research, Inc, Houston, Texas., Laquer VT; First OC Dermatology Research, Fountain Valley, California., Hanke CW; Laser & Skin Surgery Center of Indiana (The Lassi), Indianapolis, Indiana., Ozog DM; Department of Dermatology, Henry Ford Health, Detroit, Michigan; Department of Medicine, Michigan State University, East Lansing, Michigan., Schneider J; The Narrows Institute for Biomedical Research and Education, Inc., Brooklyn, New York., Markowitz O; The Narrows Institute for Biomedical Research and Education, Inc., Brooklyn, New York., Berman B; Center for Clinical and Cosmetic Research, Aventura, Florida., Nestor MS; Center for Clinical and Cosmetic Research, Aventura, Florida., Gold MH; Tennessee Clinical Research Center, Nashville, Tennessee., Munavalli GS; Dermatology, Laser & Vein Specialists of the Carolinas, Charlotte, North Carolina., Forsha DW; Jordan Valley Dermatology Center, West Jordan, Utah., Siegel DM; Veterans Affairs New York Harbor Healthcare System-Brooklyn, Brooklyn, New York., Mrohs D; Biofrontera Discovery GmbH, Leverkusen, Germany., Schmitz B; Biofrontera Discovery GmbH, Leverkusen, Germany., Schäning R; Biofrontera Discovery GmbH, Leverkusen, Germany., Pospiech N; Biofrontera Bioscience GmbH, Leverkusen, Germany., Lyons J; Biofrontera Inc., Woburn, Massachusetts., Foguet M; Biofrontera Bioscience GmbH, Leverkusen, Germany., Lübbert M; Biofrontera Discovery GmbH, Leverkusen, Germany. Electronic address: m.luebbert@bfinc.com., Lübbert H; Biofrontera Discovery GmbH, Leverkusen, Germany; Biofrontera Inc., Woburn, Massachusetts., Pariser DM; Eastern Virginia Medical School and Virginia Clinical Research, Inc., Norfolk, Virginia.
Source: Journal of the American Academy of Dermatology [J Am Acad Dermatol] 2025 Dec; Vol. 93 (6), pp. 1489-1498. Date of Electronic Publication: 2025 Aug 20.
Publication Type: Journal Article; Randomized Controlled Trial; Multicenter Study; Clinical Trial, Phase III; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Mosby Country of Publication: United States NLM ID: 7907132 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-6787 (Electronic) Linking ISSN: 01909622 NLM ISO Abbreviation: J Am Acad Dermatol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1097-6787
DOI:10.1016/j.jaad.2025.08.031