Personalized circulating tumor DNA dynamics inform survival and response to immune checkpoint blockade in recurrent/metastatic head and neck cancer.
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| Title: | Personalized circulating tumor DNA dynamics inform survival and response to immune checkpoint blockade in recurrent/metastatic head and neck cancer. |
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| Authors: | Ruiz-Torres DA; Department of Otolaryngology-Head and Neck Surgery, Massachusetts Eye and Ear, Boston, MA, USA.; Krantz Family Center for Cancer Research, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Merkin RD; Department of Otolaryngology-Head and Neck Surgery, Massachusetts Eye and Ear, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Center for Head and Neck Cancers, Massachusetts General Hospital, Boston, MA, USA., Bryan ME; Department of Otolaryngology-Head and Neck Surgery, Massachusetts Eye and Ear, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Mendel J; Department of Otolaryngology-Head and Neck Surgery, Massachusetts Eye and Ear, Boston, MA, USA., Efthymiou V; Department of Otolaryngology-Head and Neck Surgery, Massachusetts Eye and Ear, Boston, MA, USA., Roberts T; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Center for Head and Neck Cancers, Massachusetts General Hospital, Boston, MA, USA., Patel MJ; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Center for Head and Neck Cancers, Massachusetts General Hospital, Boston, MA, USA., Park JC; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Center for Head and Neck Cancers, Massachusetts General Hospital, Boston, MA, USA., Chevalier A; NeoGenomics, Inc., Fort Meyers, FL, USA., Murray C; NeoGenomics, Inc., Fort Meyers, FL, USA., Gates L; NeoGenomics, Inc., Fort Meyers, FL, USA., Pipinikas C; NeoGenomics, Inc., Fort Meyers, FL, USA., Stott SL; Krantz Family Center for Cancer Research, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Center for Engineering in Medicine & Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Fisch AS; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Department of Pathology, Massachusetts General Hospital, Boston, MA, USA., Wirth LJ; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Center for Head and Neck Cancers, Massachusetts General Hospital, Boston, MA, USA., Faden DL; Department of Otolaryngology-Head and Neck Surgery, Massachusetts Eye and Ear, Boston, MA, USA. dfaden@mgb.org.; Department of Medicine, Harvard Medical School, Boston, MA, USA. dfaden@mgb.org.; Broad Institute of MIT and Harvard, Cambridge, MA, USA. dfaden@mgb.org.; Center for Head and Neck Cancers, Massachusetts General Hospital, Boston, MA, USA. dfaden@mgb.org. |
| Source: | NPJ precision oncology [NPJ Precis Oncol] 2025 Aug 22; Vol. 9 (1), pp. 298. Date of Electronic Publication: 2025 Aug 22. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer Nature Country of Publication: England NLM ID: 101708166 Publication Model: Electronic Cited Medium: Print ISSN: 2397-768X (Print) Linking ISSN: 2397768X NLM ISO Abbreviation: NPJ Precis Oncol Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2397-768X |
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| DOI: | 10.1038/s41698-025-01084-4 |
