Multi-population genome-wide association study identifies multiple novel loci associated with asymptomatic intracranial large artery stenosis.
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| Title: | Multi-population genome-wide association study identifies multiple novel loci associated with asymptomatic intracranial large artery stenosis. |
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| Authors: | Liu M; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA., Khasiyev F; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.; Department of Neurology, University of Minnesota, Minneapolis, MN, USA., Spagnolo-Allende A; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA., Sanchez DL; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.; The Gertrude H. Sergievsky Center, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA., Andrews H; Biostatistics Department, Mailman School of Public Health, Columbia University, New York, NY, USA., Yang Q; Department of Biostatistics, School of Public Health, Boston University, Boston, MA, USA., Beiser A; Department of Biostatistics, School of Public Health, Boston University, Boston, MA, USA., Qiao Y; Johns Hopkins University School of Medicine, Baltimore, MD, USA., Romero JR; Department of Neurology, Boston University School of Medicine, Boston, MA, USA., Rundek T; Department of Neurology, University of Miami Miller School of Medicine, Miami, FL, USA.; Department of Public Health Sciences, University of Miami Miller School of Medicine, Miami, FL, USA.; Evelyn F. McKnight Brain Institute, University of Miami Miller School of Medicine, Miami, FL, USA., Brickman AM; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.; The Gertrude H. Sergievsky Center, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA., Manly JJ; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.; The Gertrude H. Sergievsky Center, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA., Elkind MS; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA., Seshadri S; Department of Neurology, Boston University School of Medicine, Boston, MA, USA.; The Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Sciences Center, San Antonio, TX, USA., Chen C; Memory Aging and Cognition Center, Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Del Brutto OH; School of Medicine and Research Center, Universidad Espíritu Santo, Samborondón, Ecuador., Hilal S; Memory Aging and Cognition Center, Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Wasserman BA; Johns Hopkins University School of Medicine, Baltimore, MD, USA.; University of Maryland School of Medicine, Baltimore, MD, USA., Tosto G; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.; The Gertrude H. Sergievsky Center, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA., Fornage M; Brown Foundation Institute of Molecular Medicine, Mc Govern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.; Human Genetics Center, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA., Gutierrez J; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA. |
| Source: | International journal of stroke : official journal of the International Stroke Society [Int J Stroke] 2026 Apr; Vol. 21 (4), pp. 515-525. Date of Electronic Publication: 2025 Aug 24. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: SAGE Publications Country of Publication: United States NLM ID: 101274068 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1747-4949 (Electronic) Linking ISSN: 17474930 NLM ISO Abbreviation: Int J Stroke Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 40851121 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Multi-population genome-wide association study identifies multiple novel loci associated with asymptomatic intracranial large artery stenosis. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Liu+M%22">Liu M</searchLink>; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Khasiyev+F%22">Khasiyev F</searchLink>; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.; Department of Neurology, University of Minnesota, Minneapolis, MN, USA.<br /><searchLink fieldCode="AU" term="%22Spagnolo-Allende+A%22">Spagnolo-Allende A</searchLink>; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Sanchez+DL%22">Sanchez DL</searchLink>; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.; The Gertrude H. Sergievsky Center, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Andrews+H%22">Andrews H</searchLink>; Biostatistics Department, Mailman School of Public Health, Columbia University, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Yang+Q%22">Yang Q</searchLink>; Department of Biostatistics, School of Public Health, Boston University, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Beiser+A%22">Beiser A</searchLink>; Department of Biostatistics, School of Public Health, Boston University, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Qiao+Y%22">Qiao Y</searchLink>; Johns Hopkins University School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Romero+JR%22">Romero JR</searchLink>; Department of Neurology, Boston University School of Medicine, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Rundek+T%22">Rundek T</searchLink>; Department of Neurology, University of Miami Miller School of Medicine, Miami, FL, USA.; Department of Public Health Sciences, University of Miami Miller School of Medicine, Miami, FL, USA.; Evelyn F. McKnight Brain Institute, University of Miami Miller School of Medicine, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Brickman+AM%22">Brickman AM</searchLink>; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.; The Gertrude H. Sergievsky Center, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Manly+JJ%22">Manly JJ</searchLink>; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.; The Gertrude H. Sergievsky Center, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Elkind+MS%22">Elkind MS</searchLink>; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Seshadri+S%22">Seshadri S</searchLink>; Department of Neurology, Boston University School of Medicine, Boston, MA, USA.; The Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Sciences Center, San Antonio, TX, USA.<br /><searchLink fieldCode="AU" term="%22Chen+C%22">Chen C</searchLink>; Memory Aging and Cognition Center, Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Del+Brutto+OH%22">Del Brutto OH</searchLink>; School of Medicine and Research Center, Universidad Espíritu Santo, Samborondón, Ecuador.<br /><searchLink fieldCode="AU" term="%22Hilal+S%22">Hilal S</searchLink>; Memory Aging and Cognition Center, Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Wasserman+BA%22">Wasserman BA</searchLink>; Johns Hopkins University School of Medicine, Baltimore, MD, USA.; University of Maryland School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Tosto+G%22">Tosto G</searchLink>; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.; The Gertrude H. Sergievsky Center, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Fornage+M%22">Fornage M</searchLink>; Brown Foundation Institute of Molecular Medicine, Mc Govern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.; Human Genetics Center, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Gutierrez+J%22">Gutierrez J</searchLink>; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101274068%22">International journal of stroke : official journal of the International Stroke Society</searchLink> [Int J Stroke] 2026 Apr; Vol. 21 (4), pp. 515-525. <i>Date of Electronic Publication: </i>2025 Aug 24. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22SAGE+Publications%22">SAGE Publications </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101274068 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1747-4949 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217474930%22">17474930 </searchLink><i>NLM ISO Abbreviation: </i>Int J Stroke <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40851121 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1177/17474930251374471 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 515 Titles: – TitleFull: Multi-population genome-wide association study identifies multiple novel loci associated with asymptomatic intracranial large artery stenosis. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Liu M – PersonEntity: Name: NameFull: Khasiyev F – PersonEntity: Name: NameFull: Spagnolo-Allende A – PersonEntity: Name: NameFull: Sanchez DL – PersonEntity: Name: NameFull: Andrews H – PersonEntity: Name: NameFull: Yang Q – PersonEntity: Name: NameFull: Beiser A – PersonEntity: Name: NameFull: Qiao Y – PersonEntity: Name: NameFull: Romero JR – PersonEntity: Name: NameFull: Rundek T – PersonEntity: Name: NameFull: Brickman AM – PersonEntity: Name: NameFull: Manly JJ – PersonEntity: Name: NameFull: Elkind MS – PersonEntity: Name: NameFull: Seshadri S – PersonEntity: Name: NameFull: Chen C – PersonEntity: Name: NameFull: Del Brutto OH – PersonEntity: Name: NameFull: Hilal S – PersonEntity: Name: NameFull: Wasserman BA – PersonEntity: Name: NameFull: Tosto G – PersonEntity: Name: NameFull: Fornage M – PersonEntity: Name: NameFull: Gutierrez J IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 04 Text: 2026 Apr Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1747-4949 Numbering: – Type: volume Value: 21 – Type: issue Value: 4 Titles: – TitleFull: International journal of stroke : official journal of the International Stroke Society Type: main |
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