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Helicobacter hepaticus promotes hepatic steatosis through CdtB-induced mitochondrial stress and lipid metabolism reprogramming.

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Title: Helicobacter hepaticus promotes hepatic steatosis through CdtB-induced mitochondrial stress and lipid metabolism reprogramming.
Authors: Jin S; Institute of Comparative Medicine, College of Veterinary Medicine, Yangzhou University, Yangzhou, China.; Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Yangzhou, China., Zhu L; Institute of Comparative Medicine, College of Veterinary Medicine, Yangzhou University, Yangzhou, China. zhuliqi@yzu.edu.cn.; Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Yangzhou, China. zhuliqi@yzu.edu.cn., Bao R; Institute of Comparative Medicine, College of Veterinary Medicine, Yangzhou University, Yangzhou, China.; Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Yangzhou, China., Yang L; Institute of Comparative Medicine, College of Veterinary Medicine, Yangzhou University, Yangzhou, China.; Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Yangzhou, China., Zhuang T; Institute of Comparative Medicine, College of Veterinary Medicine, Yangzhou University, Yangzhou, China.; Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Yangzhou, China., Lian L; MAFLD Research Center, Department of Hepatology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.; Key Laboratory of Diagnosis and Treatment for the Development of Chronic Liver Disease in Zhejiang Province, Wenzhou, China., Wang T; Institute of Comparative Medicine, College of Veterinary Medicine, Yangzhou University, Yangzhou, China.; Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Yangzhou, China., Yin J; Institute of Comparative Medicine, College of Veterinary Medicine, Yangzhou University, Yangzhou, China.; Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Yangzhou, China., Zhang S; State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China., Zhou L; Shanghai Immune Therapy Institute, Shanghai Jiaotong University School of Medicine-affiliated Renji Hospital, Shanghai, China., Zheng M; MAFLD Research Center, Department of Hepatology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China. zhengmh@wmu.edu.cn.; Key Laboratory of Diagnosis and Treatment for the Development of Chronic Liver Disease in Zhejiang Province, Wenzhou, China. zhengmh@wmu.edu.cn., Zhang Q; Institute of Comparative Medicine, College of Veterinary Medicine, Yangzhou University, Yangzhou, China. zquan@yzu.edu.cn.; Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Yangzhou, China. zquan@yzu.edu.cn.
Source: Nature communications [Nat Commun] 2025 Aug 26; Vol. 16 (1), pp. 7954. Date of Electronic Publication: 2025 Aug 26.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Helicobacter hepaticus promotes hepatic steatosis through CdtB-induced mitochondrial stress and lipid metabolism reprogramming.
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  Data: <searchLink fieldCode="AU" term="%22Jin+S%22">Jin S</searchLink>; Institute of Comparative Medicine, College of Veterinary Medicine, Yangzhou University, Yangzhou, China.; Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Yangzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhu+L%22">Zhu L</searchLink>; Institute of Comparative Medicine, College of Veterinary Medicine, Yangzhou University, Yangzhou, China. zhuliqi@yzu.edu.cn.; Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Yangzhou, China. zhuliqi@yzu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Bao+R%22">Bao R</searchLink>; Institute of Comparative Medicine, College of Veterinary Medicine, Yangzhou University, Yangzhou, China.; Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Yangzhou, China.<br /><searchLink fieldCode="AU" term="%22Yang+L%22">Yang L</searchLink>; Institute of Comparative Medicine, College of Veterinary Medicine, Yangzhou University, Yangzhou, China.; Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Yangzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhuang+T%22">Zhuang T</searchLink>; Institute of Comparative Medicine, College of Veterinary Medicine, Yangzhou University, Yangzhou, China.; Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Yangzhou, China.<br /><searchLink fieldCode="AU" term="%22Lian+L%22">Lian L</searchLink>; MAFLD Research Center, Department of Hepatology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.; Key Laboratory of Diagnosis and Treatment for the Development of Chronic Liver Disease in Zhejiang Province, Wenzhou, China.<br /><searchLink fieldCode="AU" term="%22Wang+T%22">Wang T</searchLink>; Institute of Comparative Medicine, College of Veterinary Medicine, Yangzhou University, Yangzhou, China.; Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Yangzhou, China.<br /><searchLink fieldCode="AU" term="%22Yin+J%22">Yin J</searchLink>; Institute of Comparative Medicine, College of Veterinary Medicine, Yangzhou University, Yangzhou, China.; Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Yangzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhang+S%22">Zhang S</searchLink>; State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhou+L%22">Zhou L</searchLink>; Shanghai Immune Therapy Institute, Shanghai Jiaotong University School of Medicine-affiliated Renji Hospital, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Zheng+M%22">Zheng M</searchLink>; MAFLD Research Center, Department of Hepatology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China. zhengmh@wmu.edu.cn.; Key Laboratory of Diagnosis and Treatment for the Development of Chronic Liver Disease in Zhejiang Province, Wenzhou, China. zhengmh@wmu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Zhang+Q%22">Zhang Q</searchLink>; Institute of Comparative Medicine, College of Veterinary Medicine, Yangzhou University, Yangzhou, China. zquan@yzu.edu.cn.; Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Yangzhou, China. zquan@yzu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2025 Aug 26; Vol. 16 (1), pp. 7954. <i>Date of Electronic Publication: </i>2025 Aug 26.
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