NF1-depleted ER+ breast cancers are differentially sensitive to CDK4/6 inhibitors.
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| Title: | NF1-depleted ER+ breast cancers are differentially sensitive to CDK4/6 inhibitors. |
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| Authors: | Zheng ZY; Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA.; Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA., Chen A; Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA., Jaehnig EJ; Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA., Anurag M; Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA.; Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA., Lei JT; Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA., Feng L; Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA., Wang C; Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA., Fandino D; Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA., Singh P; Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA., Kennedy H; Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA., Yadav G; Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA., Vollert CT; Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA., Tsai J; Guardant Health, Palo Alto, CA 94304, USA., Chen X; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA., Li Y; Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA.; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA., Lim B; Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA., Thompson A; Department of Surgery, Baylor College of Medicine, Houston, TX 77030, USA., Li S; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA., Foulds CE; Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA.; Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA., Zhang B; Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA., Ellis MJ; Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA.; Guardant Health, Palo Alto, CA 94304, USA., Chang EC; Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA.; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA. |
| Source: | Science translational medicine [Sci Transl Med] 2025 Aug 27; Vol. 17 (813), pp. eadq5492. Date of Electronic Publication: 2025 Aug 27. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1946-6242 |
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| DOI: | 10.1126/scitranslmed.adq5492 |
