Effects of Mediterranean diet, exercise, and their combination on body composition and liver outcomes in metabolic dysfunction-associated steatotic liver disease: a systematic review and meta-analysis of randomized controlled trials.

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Title: Effects of Mediterranean diet, exercise, and their combination on body composition and liver outcomes in metabolic dysfunction-associated steatotic liver disease: a systematic review and meta-analysis of randomized controlled trials.
Authors: Arita VA; Department of Global Public Health and Bioethics, Julius Center for Health Sciences and Primary Care, University Medical Center (UMC) Utrecht, Utrecht, The Netherlands., Cabezas MC; Department of Internal Medicine, Franciscus Gasthuis & Vlietland, Rotterdam, the Netherlands.; Julius Clinical, Zeist, the Netherlands.; Department of Internal Medicine, Department of Endocrinology, Erasmus Medical Center, Rotterdam, The Netherlands., Hernández Vargas JA; Department of Global Public Health and Bioethics, Julius Center for Health Sciences and Primary Care, University Medical Center (UMC) Utrecht, Utrecht, The Netherlands., Trujillo-Cáceres SJ; Department of Global Public Health and Bioethics, Julius Center for Health Sciences and Primary Care, University Medical Center (UMC) Utrecht, Utrecht, The Netherlands., Mendez Pernicone N; Department of Global Public Health and Bioethics, Julius Center for Health Sciences and Primary Care, University Medical Center (UMC) Utrecht, Utrecht, The Netherlands., Bridge LA; Department of Global Public Health and Bioethics, Julius Center for Health Sciences and Primary Care, University Medical Center (UMC) Utrecht, Utrecht, The Netherlands., Raeisi-Dehkordi H; Department of Global Public Health and Bioethics, Julius Center for Health Sciences and Primary Care, University Medical Center (UMC) Utrecht, Utrecht, The Netherlands., Dietvorst CAW; Department of Internal Medicine, Franciscus Gasthuis & Vlietland, Rotterdam, the Netherlands.; Department of Internal Medicine, Division of Dietetics, Erasmus Medical Center, Rotterdam, The Netherlands., Dekker R; Department of Global Public Health and Bioethics, Julius Center for Health Sciences and Primary Care, University Medical Center (UMC) Utrecht, Utrecht, The Netherlands., Uriza-Pinzón JP; Department of Global Public Health and Bioethics, Julius Center for Health Sciences and Primary Care, University Medical Center (UMC) Utrecht, Utrecht, The Netherlands., Tawfik M; Novo Nordisk, Bagsvaerd, Denmark., Berk KA; Department of Internal Medicine, Division of Dietetics, Erasmus Medical Center, Rotterdam, The Netherlands., Massoels J; Echosens, Paris, France., Driessen S; Department of Internal and Vascular Medicine, Amsterdam University Medical Center, Amsterdam, the Netherlands., Tushuizen ME; Leiden University Medical Center, Department of Gastroenterology & Hepatology, Leiden, the Netherlands., Holleboom AG; Department of Internal and Vascular Medicine, Amsterdam University Medical Center, Amsterdam, the Netherlands., Grobbee DE; Department of Global Public Health and Bioethics, Julius Center for Health Sciences and Primary Care, University Medical Center (UMC) Utrecht, Utrecht, The Netherlands.; Julius Clinical, Zeist, the Netherlands., Franco OH; Department of Global Public Health and Bioethics, Julius Center for Health Sciences and Primary Care, University Medical Center (UMC) Utrecht, Utrecht, The Netherlands., Beigrezaei S; Department of Global Public Health and Bioethics, Julius Center for Health Sciences and Primary Care, University Medical Center (UMC) Utrecht, Utrecht, The Netherlands. S.Beigrezaei@umcutrecht.nl.
Corporate Authors: GRIPonMASH Consortium
Source: BMC medicine [BMC Med] 2025 Aug 27; Vol. 23 (1), pp. 502. Date of Electronic Publication: 2025 Aug 27.
Publication Type: Journal Article; Meta-Analysis; Systematic Review
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101190723 Publication Model: Electronic Cited Medium: Internet ISSN: 1741-7015 (Electronic) Linking ISSN: 17417015 NLM ISO Abbreviation: BMC Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1741-7015
DOI:10.1186/s12916-025-04320-7