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Metastasis-Initiating Osteosarcoma Subpopulations Establish Paracrine Interactions with Lung and Tumor Cells to Create a Metastatic Niche.

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Title: Metastasis-Initiating Osteosarcoma Subpopulations Establish Paracrine Interactions with Lung and Tumor Cells to Create a Metastatic Niche.
Authors: Reinecke JB; Department of Hematology, Oncology, and Bone Marrow Transplant, Nationwide Children's Hospital, Columbus, Ohio., Jimenez Garcia L; Center for Childhood Cancer Research, Abigail Wexner Research Institute, Nationwide Children's Hospital, Columbus, Ohio.; Molecular, Cellular, and Developmental Biology Program, The Ohio State University, Columbus, Ohio., Saraf AJ; Department of Hematology, Oncology, and Bone Marrow Transplant, Riley Children's Hospital, Indianapolis, Indiana.; Indiana University Department of Pediatrics, Indianapolis, Indiana., Hinckley J; Battelle, Columbus, Ohio., Gross AC; Center for Childhood Cancer Research, Abigail Wexner Research Institute, Nationwide Children's Hospital, Columbus, Ohio., Le Pommellet H; The Ohio State University College of Veterinary Medicine, Columbus, Ohio., Gutpell KM; Department of Hematology, Oncology, and Bone Marrow Transplant, Nationwide Children's Hospital, Columbus, Ohio.; Center for Childhood Cancer Research, Abigail Wexner Research Institute, Nationwide Children's Hospital, Columbus, Ohio., Cam M; Institute for Genomic Medicine, Nationwide Children's Hospital, Columbus, Ohio., Cannon MV; Center for Childhood Cancer Research, Abigail Wexner Research Institute, Nationwide Children's Hospital, Columbus, Ohio., Gust MJ; Center for Childhood Cancer Research, Abigail Wexner Research Institute, Nationwide Children's Hospital, Columbus, Ohio., Vatelle S; Center for Childhood Cancer Research, Abigail Wexner Research Institute, Nationwide Children's Hospital, Columbus, Ohio., Gryder BE; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, Ohio., Dries R; Section of Hematology and Medical Oncology, Boston University School of Medicine and Boston Medical Center, Boston, Massachusetts.; Division of Computational Biomedicine, Boston University School of Medicine, Boston, Massachusetts., Roberts RD; Department of Hematology, Oncology, and Bone Marrow Transplant, Nationwide Children's Hospital, Columbus, Ohio.; Center for Childhood Cancer Research, Abigail Wexner Research Institute, Nationwide Children's Hospital, Columbus, Ohio.; The Ohio State University James Comprehensive Cancer Center, Columbus, Ohio.
Source: Cancer research [Cancer Res] 2025 Nov 14; Vol. 85 (22), pp. 4341-4358.
Publication Type: Journal Article
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Metastasis-Initiating Osteosarcoma Subpopulations Establish Paracrine Interactions with Lung and Tumor Cells to Create a Metastatic Niche.
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              Text: 2025 Nov 14
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