Identification of cystatin C as a new marker of glomerular filtration rate, and of shrunken pore syndrome - a new kidney disorder defining selective glomerular hypofiltration syndromes - calls for expansion of the international KDIGO guidelines.

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Title: Identification of cystatin C as a new marker of glomerular filtration rate, and of shrunken pore syndrome - a new kidney disorder defining selective glomerular hypofiltration syndromes - calls for expansion of the international KDIGO guidelines.
Authors: Åkesson A; Division of Occupational and Environmental Medicine, Lund University, Lund, Sweden.; Clinical Studies Sweden - Forum South, Skåne University Hospital, Lund, Sweden., Öberg C; Department of Clinical Sciences Lund, Lund University, Lund, Sweden.; Department of Nephrology, Skåne University Hospital, Lund, Sweden., Malmgren L; Department of Clinical Sciences Malmö, Clinical and Molecular Osteoporosis Research Unit, Lund University, Malmö, Sweden.; Department of Geriatrics, Skåne University Hospital, Malmö, Sweden., Nilsson C; Department of Clinical Sciences, Malmö, Lund University, Sweden Lund., Itoh Y; Clinical Laboratory, Eiju General Hospital, Life Extension Research Institute, Tokyo, Japan., Blirup-Jensen S; Division of Clinical Chemistry and Pharmacology, Department of Laboratory Medicine, Lund University, Lund, Sweden., Lindström V; Division of Clinical Chemistry and Pharmacology, Department of Laboratory Medicine, Lund University, Lund, Sweden., Abrahamson M; Division of Clinical Chemistry and Pharmacology, Department of Laboratory Medicine, Lund University, Lund, Sweden., Leion F; Division of Clinical Chemistry and Pharmacology, Department of Laboratory Medicine, Lund University, Lund, Sweden., Olafsson I; Department of Clinical Biochemistry, Landspitali - National University Hospital of Iceland, Reykjavik, Iceland., Bjursten H; Department of Cardiothoracic Surgery, Skåne University Hospital, Lund University, Lund, Sweden., Grubb D; Department of Cardiothoracic Surgery, Skåne University Hospital, Lund University, Lund, Sweden., Herou E; Department of Cardiothoracic Surgery, Skåne University Hospital, Lund University, Lund, Sweden., Dardashti A; Department of Cardiothoracic Surgery, Skåne University Hospital, Lund University, Lund, Sweden., Sigurjonsson J; Department of Cardiothoracic Surgery, Skåne University Hospital, Lund University, Lund, Sweden., Xhakollari L; Department of Clinical Sciences, Malmö, Lund University, Sweden Lund.; Department of Nephrology, Skåne University Hospital, Malmö, Sweden., Laucyte-Cibulskiene A; Department of Clinical Sciences, Malmö, Lund University, Sweden Lund., Pottel H; Department of Public Health and Primary Care, KULeuven Campus Kulak Kortrijk, Kortrijk, Belgium., Strevens H; Department of Obstetrics and Gynecology, Lund University, Skåne University Hospital, Lund, Sweden., Damm D; Department of Obstetrics and Gynecology, Lund University, Skåne University Hospital, Lund, Sweden., Förnvik Jonsson M; Department of Clinical Chemistry and Pharmacology, Skåne University Hospital, Lund, Sweden., Siódmiak J; Department of Laboratory Medicine, Faculty of Pharmacy, Ludwik Rydygier Collegium Medicum (Nicolaus Copernicus University in Torun), Bydgoszcz, Poland., Ärnlöv J; Department of Neurobiology, Care Sciences and Society (NVS), Family Medicine and Primary Care Unit, Karolinska Institute, Huddinge, Sweden.; School of Health and Social Studies, Dalarna University, Falun, Sweden., Larsson A; Department of Medical Sciences, Clinical Chemistry, Uppsala University Hospital, Uppsala, Sweden., Åkerfeldt T; Department of Medical Sciences, Clinical Chemistry, Uppsala University Hospital, Uppsala, Sweden., Kultima K; Department of Medical Sciences, Clinical Chemistry, Uppsala University Hospital, Uppsala, Sweden., Ridefelt P; Department of Medical Sciences, Clinical Chemistry, Uppsala University Hospital, Uppsala, Sweden., Helmersson-Karlqvist J; Department of Medical Sciences, Clinical Chemistry, Uppsala University Hospital, Uppsala, Sweden., Magnusson M; Department of Clinical Sciences, Lund University, Malmö, Sweden.; Department of Cardiology, Skåne University Hospital, Malmö, Sweden.; Wallenberg Center for Molecular Medicine, Lund University, Lund, Sweden.; Hypertension in Africa Research Team (HART), North West University, Potchefstroom, South Africa., Hansson M; Department of Laboratory Medicine, Division of Clinical Chemistry, Karolinska Institutet, Stockholm and Department of Clinical Chemistry, Karolinska University Hospital, Stockholm, Sweden., Sjöström A; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm and Department of Clinical Chemistry, Karolinska University Hospital, Stockholm, Sweden., Soveri I; Department of Medical Sciences, Nephrology Uppsala University Hospital, Uppsala, Sweden., Tenstad O; Department of Biomedicine, University of Bergen, Bergen, Norway., Mårtensson J; Department of Physiology and Pharmacology, Section of Anaesthesia and Intensive Care, Karolinska Institute, Stockholm, Sweden., Elinder CG; Division of Renal Medicine, Department of Clinical Intervention, and Technology, Karolinska University Hospital and Karolinska Institute, Stockholm, Sweden., Risch L; Faculty of Medical Sciences, Private University in the Principality of Liechtenstein, Triesen, Liechtenstein.; University Institute of Clinical Chemistry, University Hospital and University of Bern, Inselspital, Bern, Switzerland., Risch M; Central Laboratory, Cantonal Hospital Graubünden, Chur, Switzerland.; Dr. Risch Medical Laboratory, Sonic Suisse, Vaduz, Liechtenstein., Hansson LO; Department of Medical Sciencies, Clinical Chemistry, Uppsala University Hospital, Uppsala, Sweden., Price CP; Emeritus Professor in Clinical Biochemistry, Queen Mary, University of London, London, UK., Nyman U; Department of Translational Medicine, Division of Medical Radiology, University of Lund, Malmö, Sweden., Björk J; Division of Occupational and Environmental Medicine, Lund University, Lund, Sweden.; Clinical Studies Sweden - Forum South, Skåne University Hospital, Lund, Sweden., Delanaye P; Department of Nephrology-Dialysis-Transplantation, University of Liège, CHU Sart Tilman, Belgium.; GIGA Metabolism and Cardiovascular Biology, Universityof Liège, Liège, Belgium.; Department of Nephrology-Dialysis-Apheresis, Hôpital Universitaire Carémeau, Nîmes, France., Bökenkamp A; Department of Paediatric Nephrology, Emma Children's Hospital, Amsterdam UMC, The Netherlands., Christensson A; Department of Nephrology, Skåne University Hospital, Lund University, Malmö, Sweden., Grubb A; Division of Clinical Chemistry and Pharmacology, Department of Laboratory Medicine, Lund University, Lund, Sweden.
Source: Scandinavian journal of clinical and laboratory investigation [Scand J Clin Lab Invest] 2025; Vol. 85 (6), pp. 409-419. Date of Electronic Publication: 2025 Sep 01.
Publication Type: Journal Article; Review
Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 0404375 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1502-7686 (Electronic) Linking ISSN: 00365513 NLM ISO Abbreviation: Scand J Clin Lab Invest Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1502-7686
DOI:10.1080/00365513.2025.2546320