Multiple myeloma associated long non-coding RNA PLUM confers chemoresistance by enhancing PRC2 mediated UPR pathway activation.
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| Title: | Multiple myeloma associated long non-coding RNA PLUM confers chemoresistance by enhancing PRC2 mediated UPR pathway activation. |
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| Authors: | Deka K; School of Biological Sciences (SBS), Nanyang Technological University (NTU), Singapore, Singapore., Carter JM; School of Biological Sciences (SBS), Nanyang Technological University (NTU), Singapore, Singapore., Bahai A; School of Biological Sciences (SBS), Nanyang Technological University (NTU), Singapore, Singapore., Ang DA; School of Biological Sciences (SBS), Nanyang Technological University (NTU), Singapore, Singapore., Sim N; School of Biological Sciences (SBS), Nanyang Technological University (NTU), Singapore, Singapore., Chong HY; Cancer Science Institute of Singapore, National University of Singapore (NUS), Singapore, Singapore., Lee GHB; School of Biological Sciences (SBS), Nanyang Technological University (NTU), Singapore, Singapore., Tan SM; School of Biological Sciences (SBS), Nanyang Technological University (NTU), Singapore, Singapore., Chng WJ; Cancer Science Institute of Singapore, National University of Singapore (NUS), Singapore, Singapore.; Department of Medicine, Yong Loo Lin School of Medicine, NUS, Singapore, Singapore.; NUS Centre for Cancer Research, Centre for Translational Medicine, Singapore, Singapore.; Department of Hematology-Oncology, National University Cancer Institute of Singapore (NCIS), The National University Health System (NUHS), Singapore, Singapore., Kappei D; Cancer Science Institute of Singapore, National University of Singapore (NUS), Singapore, Singapore.; NUS Centre for Cancer Research, Centre for Translational Medicine, Singapore, Singapore.; Department of Biochemistry, Yong Loo Lin School of Medicine, NUS, Singapore, Singapore., Li Y; School of Biological Sciences (SBS), Nanyang Technological University (NTU), Singapore, Singapore. liyh@ntu.edu.sg.; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Proteos, Singapore, Singapore. liyh@ntu.edu.sg. |
| Source: | Nature communications [Nat Commun] 2025 Sep 01; Vol. 16 (1), pp. 8155. Date of Electronic Publication: 2025 Sep 01. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-025-63256-x |
