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Exploring topical atorvastatin hyalurosomal gel as an adjuvant for reducing systemic corticosteroid dosage: a randomized clinical trial in severe oral lichen planus patients.

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Title: Exploring topical atorvastatin hyalurosomal gel as an adjuvant for reducing systemic corticosteroid dosage: a randomized clinical trial in severe oral lichen planus patients.
Authors: Elsayed M; Clinical Pharmacy Department, Faculty of Pharmacy, Modern University for Technology & Information, Cairo, Egypt., Essawy A; Clinical Pharmacy Department, Faculty of Pharmacy, Modern University for Technology & Information, Cairo, Egypt., Ismail RM; Oral Medicine, Periodontology and Oral Diagnosis, College of Oral and Dental Surgery, Misr University for Science and Technology, Cairo, Egypt., Gamil Y; Department of Oral Medicine and Periodontology, Faculty of Dentistry, Modern University for Technology & Information, Cairo, Egypt., Hamed MG; Otolaryngology, Faculty of Medicine, Helwan University, Cairo, Egypt., Elsabaawy D; Clinical Pharmacy Department, Faculty of Pharmacy, Menofia University, Cairo, Egypt., Abdelhakeem E; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Cairo University, Cairo, Egypt. eman.abdelhakeem@pharma.cu.edu.eg., Hegazy D; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Cairo University, Cairo, Egypt., Abd-Elal RMA; Pharmaceutics and Drug Manufacturing Department, Faculty of Pharmacy, Modern University for Technology and Information (MTI), Cairo, 11571, Egypt.
Source: Drug delivery and translational research [Drug Deliv Transl Res] 2026 May; Vol. 16 (5), pp. 1495-1516. Date of Electronic Publication: 2025 Sep 05.
Publication Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 101540061 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2190-3948 (Electronic) Linking ISSN: 2190393X NLM ISO Abbreviation: Drug Deliv Transl Res Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2190-3948
DOI:10.1007/s13346-025-01956-z