Organelle stresses and energetic metabolisms promote endothelial-to-mesenchymal transition and fibrosis via upregulating FOSB and MEOX1 in Alzheimer's disease.

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Title: Organelle stresses and energetic metabolisms promote endothelial-to-mesenchymal transition and fibrosis via upregulating FOSB and MEOX1 in Alzheimer's disease.
Authors: Saaoud F; Department of Cardiovascular Sciences, Lewis Katz School of Medicine, Lemole Center for Integrated Lymphatics and Vascular Research, Temple University, Philadelphia, PA, United States., Ben Issa M; Department of Cardiovascular Sciences, Lewis Katz School of Medicine, Lemole Center for Integrated Lymphatics and Vascular Research, Temple University, Philadelphia, PA, United States., Liu L; Department of Cardiovascular Sciences, Lewis Katz School of Medicine, Center for Metabolic Disease Research and Thrombosis Research, Temple University, Philadelphia, PA, United States., Xu K; Department of Cardiovascular Sciences, Lewis Katz School of Medicine, Lemole Center for Integrated Lymphatics and Vascular Research, Temple University, Philadelphia, PA, United States., Lu Y; Department of Cardiovascular Sciences, Lewis Katz School of Medicine, Lemole Center for Integrated Lymphatics and Vascular Research, Temple University, Philadelphia, PA, United States., Shao Y; Department of Cardiovascular Sciences, Lewis Katz School of Medicine, Lemole Center for Integrated Lymphatics and Vascular Research, Temple University, Philadelphia, PA, United States., Han B; Department of Cardiovascular Sciences, Lewis Katz School of Medicine, Lemole Center for Integrated Lymphatics and Vascular Research, Temple University, Philadelphia, PA, United States., Jiang X; Department of Cardiovascular Sciences, Lewis Katz School of Medicine, Lemole Center for Integrated Lymphatics and Vascular Research, Temple University, Philadelphia, PA, United States.; Department of Cardiovascular Sciences, Lewis Katz School of Medicine, Center for Metabolic Disease Research and Thrombosis Research, Temple University, Philadelphia, PA, United States., Liu X; Department of Cardiovascular Sciences, Lewis Katz School of Medicine, Lemole Center for Integrated Lymphatics and Vascular Research, Temple University, Philadelphia, PA, United States., Gillespie A; Section of Nephrology, Hypertension, and Kidney Transplantation, Department of Medicine, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, United States., Luo JJ; Department of Neurology, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, United States., Martinez L; DeWitt Daughtry Family Department of Surgery, Leonard M. Miller School of Medicine, University of Miami, Miami, FL, United States., Vazquez-Padron R; DeWitt Daughtry Family Department of Surgery, Leonard M. Miller School of Medicine, University of Miami, Miami, FL, United States., Mohsin S; Lewis Katz School of Medicine, Aging+Cardiovascular Discovery Center, Temple University, Philadelphia, PA, United States., Kosmider B; Lewis Katz School of Medicine, Center for Inflammation and Lung Research, Alzheimer's Center, Temple University, Philadelphia, PA, United States., Wang H; Department of Cardiovascular Sciences, Lewis Katz School of Medicine, Center for Metabolic Disease Research and Thrombosis Research, Temple University, Philadelphia, PA, United States., Fossati S; Lewis Katz School of Medicine, Alzheimer's Center, Temple University, Philadelphia, PA, United States., Yang X; Department of Cardiovascular Sciences, Lewis Katz School of Medicine, Lemole Center for Integrated Lymphatics and Vascular Research, Temple University, Philadelphia, PA, United States.; Department of Cardiovascular Sciences, Lewis Katz School of Medicine, Center for Metabolic Disease Research and Thrombosis Research, Temple University, Philadelphia, PA, United States.
Source: Frontiers in molecular neuroscience [Front Mol Neurosci] 2025 Aug 22; Vol. 18, pp. 1605012. Date of Electronic Publication: 2025 Aug 22 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation Country of Publication: Switzerland NLM ID: 101477914 Publication Model: eCollection Cited Medium: Print ISSN: 1662-5099 (Print) Linking ISSN: 16625099 NLM ISO Abbreviation: Front Mol Neurosci Subsets: In Process
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  Data: Organelle stresses and energetic metabolisms promote endothelial-to-mesenchymal transition and fibrosis via upregulating FOSB and MEOX1 in Alzheimer's disease.
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  Data: <searchLink fieldCode="AU" term="%22Saaoud+F%22">Saaoud F</searchLink>; Department of Cardiovascular Sciences, Lewis Katz School of Medicine, Lemole Center for Integrated Lymphatics and Vascular Research, Temple University, Philadelphia, PA, United States.<br /><searchLink fieldCode="AU" term="%22Ben+Issa+M%22">Ben Issa M</searchLink>; Department of Cardiovascular Sciences, Lewis Katz School of Medicine, Lemole Center for Integrated Lymphatics and Vascular Research, Temple University, Philadelphia, PA, United States.<br /><searchLink fieldCode="AU" term="%22Liu+L%22">Liu L</searchLink>; Department of Cardiovascular Sciences, Lewis Katz School of Medicine, Center for Metabolic Disease Research and Thrombosis Research, Temple University, Philadelphia, PA, United States.<br /><searchLink fieldCode="AU" term="%22Xu+K%22">Xu K</searchLink>; Department of Cardiovascular Sciences, Lewis Katz School of Medicine, Lemole Center for Integrated Lymphatics and Vascular Research, Temple University, Philadelphia, PA, United States.<br /><searchLink fieldCode="AU" term="%22Lu+Y%22">Lu Y</searchLink>; Department of Cardiovascular Sciences, Lewis Katz School of Medicine, Lemole Center for Integrated Lymphatics and Vascular Research, Temple University, Philadelphia, PA, United States.<br /><searchLink fieldCode="AU" term="%22Shao+Y%22">Shao Y</searchLink>; Department of Cardiovascular Sciences, Lewis Katz School of Medicine, Lemole Center for Integrated Lymphatics and Vascular Research, Temple University, Philadelphia, PA, United States.<br /><searchLink fieldCode="AU" term="%22Han+B%22">Han B</searchLink>; Department of Cardiovascular Sciences, Lewis Katz School of Medicine, Lemole Center for Integrated Lymphatics and Vascular Research, Temple University, Philadelphia, PA, United States.<br /><searchLink fieldCode="AU" term="%22Jiang+X%22">Jiang X</searchLink>; Department of Cardiovascular Sciences, Lewis Katz School of Medicine, Lemole Center for Integrated Lymphatics and Vascular Research, Temple University, Philadelphia, PA, United States.; Department of Cardiovascular Sciences, Lewis Katz School of Medicine, Center for Metabolic Disease Research and Thrombosis Research, Temple University, Philadelphia, PA, United States.<br /><searchLink fieldCode="AU" term="%22Liu+X%22">Liu X</searchLink>; Department of Cardiovascular Sciences, Lewis Katz School of Medicine, Lemole Center for Integrated Lymphatics and Vascular Research, Temple University, Philadelphia, PA, United States.<br /><searchLink fieldCode="AU" term="%22Gillespie+A%22">Gillespie A</searchLink>; Section of Nephrology, Hypertension, and Kidney Transplantation, Department of Medicine, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, United States.<br /><searchLink fieldCode="AU" term="%22Luo+JJ%22">Luo JJ</searchLink>; Department of Neurology, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, United States.<br /><searchLink fieldCode="AU" term="%22Martinez+L%22">Martinez L</searchLink>; DeWitt Daughtry Family Department of Surgery, Leonard M. Miller School of Medicine, University of Miami, Miami, FL, United States.<br /><searchLink fieldCode="AU" term="%22Vazquez-Padron+R%22">Vazquez-Padron R</searchLink>; DeWitt Daughtry Family Department of Surgery, Leonard M. Miller School of Medicine, University of Miami, Miami, FL, United States.<br /><searchLink fieldCode="AU" term="%22Mohsin+S%22">Mohsin S</searchLink>; Lewis Katz School of Medicine, Aging+Cardiovascular Discovery Center, Temple University, Philadelphia, PA, United States.<br /><searchLink fieldCode="AU" term="%22Kosmider+B%22">Kosmider B</searchLink>; Lewis Katz School of Medicine, Center for Inflammation and Lung Research, Alzheimer's Center, Temple University, Philadelphia, PA, United States.<br /><searchLink fieldCode="AU" term="%22Wang+H%22">Wang H</searchLink>; Department of Cardiovascular Sciences, Lewis Katz School of Medicine, Center for Metabolic Disease Research and Thrombosis Research, Temple University, Philadelphia, PA, United States.<br /><searchLink fieldCode="AU" term="%22Fossati+S%22">Fossati S</searchLink>; Lewis Katz School of Medicine, Alzheimer's Center, Temple University, Philadelphia, PA, United States.<br /><searchLink fieldCode="AU" term="%22Yang+X%22">Yang X</searchLink>; Department of Cardiovascular Sciences, Lewis Katz School of Medicine, Lemole Center for Integrated Lymphatics and Vascular Research, Temple University, Philadelphia, PA, United States.; Department of Cardiovascular Sciences, Lewis Katz School of Medicine, Center for Metabolic Disease Research and Thrombosis Research, Temple University, Philadelphia, PA, United States.
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  Data: <searchLink fieldCode="JN" term="%22101477914%22">Frontiers in molecular neuroscience</searchLink> [Front Mol Neurosci] 2025 Aug 22; Vol. 18, pp. 1605012. <i>Date of Electronic Publication: </i>2025 Aug 22 (<i>Print Publication: </i>2025).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Research+Foundation%22">Frontiers Research Foundation </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101477914 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Print <i>ISSN: </i>1662-5099 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216625099%22">16625099 </searchLink><i>NLM ISO Abbreviation: </i>Front Mol Neurosci <i>Subsets: </i>In Process
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        Value: 10.3389/fnmol.2025.1605012
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              Text: 2025 Aug 22
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